Idiopathic Granulomatous Mastitis: Imaging Findings and Outcomes with Nonsteroidal Treatment in a Predominantly Hispanic Population.

Autor:	Rizzo L; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Hovanessian-Larsen L; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Yamashita M; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Lei X; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Cen S; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Choi J; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Lee T; Department of Pathology, Keck School of Medicine, University of California, Los Angeles, CA,  USA., Lee S; Department of Radiology, Keck School of Medicine, University of California, Los Angeles, CA,  USA.
Jazyk:	angličtina
Zdroj:	Journal of breast imaging [J Breast Imaging] 2024 Sep 04. Date of Electronic Publication: 2024 Sep 04.
DOI:	10.1093/jbi/wbae051
Abstrakt:	Objective: We describe the demographics, clinical presentation, imaging findings, and treatment response among 235 cases of biopsy-proven idiopathic granulomatous mastitis (IGM) at a single institution. Methods: An institutional review board-approved retrospective search of the breast imaging database was performed to select patients with biopsy-proven IGM between 2017 and 2022. Retrospective review evaluated clinical presentation, imaging findings with US and mammography, and treatment recommendations (antibiotics, nonsteroidal anti-inflammatory drugs [NSAIDs], warm compresses, or observation only). Response to treatment was evaluated on follow-up US. A favorable treatment response was a decrease in size or resolution of disease on follow-up imaging. Statistical analysis using Poisson regression was performed to evaluate the clinical outcomes associated with each treatment. Results: A total of 235 patients met the selection criteria with a mean age of 38 years (18 to 68). The majority of patients were Hispanic (95%, 223/235). Of all patients, 75.3% (177/235) received treatment (consisting of 1 or any combination of antibiotics, NSAIDs, warm compresses), 24.7% (58/235) were treated with observation, 78.7% (185/235) returned for follow-up imaging, and 21.3% (50/235) were lost to follow-up. Of those with follow-up imaging, disease improvement was seen in 70.3% (102/145) of patients who received treatment compared with 72.5% (29/40) of patients treated by observation alone. Multivariate analysis further showed no difference in clinical outcomes among the treatment of unifocal, multifocal, or recurrent IGM. Conclusion: Nonsteroidal treatment of IGM showed no significant improvement on follow-up imaging compared to treatment with observation alone in a predominantly Hispanic patient population. (© Society of Breast Imaging 2024. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Databáze:	MEDLINE
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