A modern approach to multiple pulmonary resections in children with recurrent metastatic pulmonary disease.

Autor: Shah NR; Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Williams KM; Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Stoll T; Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Heider A; Department of Pathology, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Opipari VP; Department of Hematology/Oncology, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Jasty Rao R; Department of Hematology/Oncology, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Newman EA; Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Ehrlich PF; Section of Pediatric Surgery, C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Geiger JD; Department of Pediatric Surgery, Nationwide Children's Hospital, Toledo, Ohio, USA.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Nov; Vol. 71 (11), pp. e31304. Date of Electronic Publication: 2024 Sep 03.
DOI: 10.1002/pbc.31304
Abstrakt: Implications of repeated resections of pulmonary metastasis (PM) are not well documented in the modern era. Fifteen children underwent two (n = 8), three (n = 3), or four or more (n = 3) resections (total = 38 procedures), most commonly for osteosarcoma (71%). Operative approach included muscle-sparing thoracotomy (71%), non-muscle-sparing thoracotomy (18%), and video-assisted thoracoscopy (11%). Median resected nodules per procedure was four (range = 1-95). Prolonged air leaks were the most common postoperative complication (29%). Median hospital stay was 4 days, and no children were discharged with or have required oxygen. Event-free survival is 67% at median follow-up time of 54 months, with an overall survival rate of 64%. Repeat resection of PM appears to be well tolerated, without prolonged hospital stays or compromised pulmonary function.
(© 2024 The Author(s). Pediatric Blood & Cancer published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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