Antibiotic resistant bacteria and antibiotic resistance genes as contaminants of emerging concern: Occurrences, impacts, mitigations and future guidelines.

Autor: Cedeño-Muñoz JS; Departamento de Procesos Químicos, Biotecnología y Alimentos, Facultad de Ingenierías y Ciencias Aplicadas, Universidad Técnica de Manabí, Portoviejo, Ecuador., Aransiola SA; Department of Microbiology, Faculty of Science, University of Abuja, PMB 117, Abuja, Nigeria., Reddy KV; Center for Biotechnology, University College of Engineering Science and Technology, Hyderabad, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad 500085, Telangana, India., Ranjit P; Center for Biotechnology, University College of Engineering Science and Technology, Hyderabad, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad 500085, Telangana, India., Victor-Ekwebelem MO; Department of Microbiology, Alex Ekwueme Federal University, Ndufu-Alike, PMB 1010, Abakaliki, Nigeria., Oyedele OJ; Bioresources Development Centre, National Biotechnology Development Agency, Ogbomoso, Nigeria., Pérez-Almeida IB; Center for Sustainable Development Studies (CEDS), Ecotec University, Samborondón, Ecuador. Electronic address: iperez@ecotec.edu.ec., Maddela NR; Departamento de Ciencias Biológicas, Facultad de Ciencias de la Salud, Universidad Técnica de Manabí, Portoviejo 130105, Ecuador. Electronic address: raju.maddela@utm.edu.ec., Rodríguez-Díaz JM; Departamento de Procesos Químicos, Biotecnología y Alimentos, Facultad de Ingenierías y Ciencias Aplicadas, Universidad Técnica de Manabí, Portoviejo, Ecuador. Electronic address: joan.rodriguez@utm.edu.ec.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Nov 20; Vol. 952, pp. 175906. Date of Electronic Publication: 2024 Sep 01.
DOI: 10.1016/j.scitotenv.2024.175906
Abstrakt: Antibiotic resistance, driven by the proliferation of antibiotic resistance genes (ARGs) and antibiotic resistance bacteria (ARBs), has emerged as a pressing global health concern. Antimicrobial resistance is exacerbated by the widespread use of antibiotics in agriculture, aquaculture, and human medicine, leading to their accumulation in various environmental compartments such as soil, water, and sediments. The presence of ARGs in the environment, particularly in municipal water, animal husbandry, and hospital environments, poses significant risks to human health, as they can be transferred to potential human pathogens. Current remediation strategies, including the use of pyroligneous acid, coagulants, advanced oxidation, and bioelectrochemical systems, have shown promising results in reducing ARGs and ARBs from soil and water. However, these methods come with their own set of challenges, such as the need for elevated base levels in UV-activated persulfate and the long residence period required for photocatalysts. The future of combating antibiotic resistance lies in the development of standardized monitoring techniques, global collaboration, and the exploration of innovative remediation methods. Emphasis on combination therapies, advanced oxidation processes, and monitoring horizontal gene transfer can pave the way for a comprehensive approach to mitigate the spread of antibiotic resistance in the environment.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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