Outcomes of surgical correction of Peyronie's disease with plaque excision and grafting: Comparison of testicular tunica vaginalis graft versus bovine pericardium graft.

Autor:	Eslahi A; Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.; Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran., Ahmed F; Urology Research Center, Al-Thora General Hospital, Department of Urology, School of Medicine, Ibb University of Medical Sciences, Ibb, Yemen., Askarpour MR; Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Nikbakht HA; Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran., Shamohammadi I; Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Ghasemi P; Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Alimardani H; Department of Urology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Ebrahimi B; Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Jazyk:	angličtina
Zdroj:	Asian journal of urology [Asian J Urol] 2024 Jul; Vol. 11 (3), pp. 497-503. Date of Electronic Publication: 2023 Aug 02.
DOI:	10.1016/j.ajur.2023.03.005
Abstrakt:	Objective: Peyronie's disease (PD) is an abnormal wound healing in the penile tunica albuginea. After fibrotic plaque excision, different graft materials have been used to repair the defects, but the optimal graft remains unknown. This study aimed to compare the functional outcomes of testicular tunica vaginalis grafts and bovine pericardium grafts in patients with severe PD. Methods: A retrospective comparative study was conducted on 33 PD patients undergoing partial plaque excision and grafting from September 2015 to May 2021. The patients were divided into two groups depending on the type of graft used. For 15 patients in Group B, testicular tunica vaginalis grafts were used to repair the defect, while for 18 patients in Group A, bovine pericardium grafts were used. Data of the patient's age, comorbidities, sexual function, penile curvature, postoperative complications, need for further treatment, change in penile length, and satisfaction were gathered and compared between the groups. Sexual function was evaluated using the 5-item version of the International Index of Erectile Function (IIEF-5), and a functional less than 20-degree penile curvature after surgery was considered a successful intervention. Results: There was no difference in age, comorbidities, degree of curvature, perioperative IIEF-5, operative time, plaque size, or complication rates. After surgery, a statistically significant improvement in curvature degree ( p <0.05) and satisfactory penile appearance ( p <0.05) were seen in both groups without any superiority between the two groups ( p =0.423 and p =0.840, respectively). With a 30-month follow-up, the IIEF-5 was consistent in both groups, with no statistical significance between the groups ( p =0.492). The main change in penile length during the operation was increased and still positive in the last follow-up in both groups without statistical significance ( p =0.255 and p =0.101, respectively). Conclusion: Partial plaque excision and corporoplasty with both testicular tunica vaginalis or bovine pericardium grafts are equally effective in treating males with clinically significant PD. Competing Interests: The authors declare no conflict of interest. (© 2024 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V.)
Databáze:	MEDLINE
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