Differential Sensing Approach as a Pattern-based Discrimination for Biological Samples.

Autor: Jo SB; Department of Pharmacology, Korea University College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.; Department of Urology, Korea University College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea., Lee JH; Department of Pharmacology, Korea University College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea., Lee J; Department of Pharmaceutical Sciences, Northestern University, 360 Huntington Avenue, Boston, MA-02115, USA., Oh MM; Department of Urology, Korea University College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea., Lee JS; Department of Pharmacology, Korea University College of Medicine, Korea University, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Jazyk: angličtina
Zdroj: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Oct 28; Vol. 30 (60), pp. e202402871. Date of Electronic Publication: 2024 Oct 23.
DOI: 10.1002/chem.202402871
Abstrakt: The differential sensing approach uses fingerprint patterning to distinguish uncharacterized biological samples. Inspired by natural sensory systems, an array of cross-reactive sensors generates unique response fingerprint depending on the samples. Until today, this array system has been developed using various materials, including the library of surface-charged nanoparticles and chemosensors. Many differential array systems have demonstrated accurate identification of bacterial species, viral subtypes, and cancer cells, as well as distinguishing disease states in blood or urine. This capability is particularly important for distinguishing between normal and abnormal states when specific marker molecules have not yet been identified, providing a powerful diagnostic tool. In this concept, we summarized representative outcomes of differential sensing applications for biological sample discrimination.
(© 2024 The Author(s). Chemistry - A European Journal published by Wiley-VCH GmbH.)
Databáze: MEDLINE
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