Effects of combined exposure to fine particulate matter and cold waves and on IHD hospitalizations at low and high altitudes.

Autor: Ning Z; Department of Public Health, Qinghai University Medical College, Xining, Qinghai 810016, China., Ma Y; Qinghai Institute of Health Sciences, Xining, Qinghai 810016, China. Electronic address: 1258597810@qq.com., He S; Xining Centre for Disease Control and Prevention, Xining, Qinghai 810000, China. Electronic address: hehe3991391@126.com., Li G; Department of Public Health, Qinghai University Medical College, Xining, Qinghai 810016, China., Hua X; Department of Public Health, Qinghai University Medical College, Xining, Qinghai 810016, China., Ma C; Xining Centre for Disease Control and Prevention, Xining, Qinghai 810000, China., Wu J; Xining Centre for Disease Control and Prevention, Xining, Qinghai 810000, China.
Jazyk: angličtina
Zdroj: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Sep 15; Vol. 283, pp. 116977. Date of Electronic Publication: 2024 Aug 30.
DOI: 10.1016/j.ecoenv.2024.116977
Abstrakt: Climate change and air pollution are major challenges facing the world today. Cold waves and air pollution significantly impact ischemic heart disease (IHD), but the extent of these effects at different altitudes remains unclear, especially their interactions. We collected daily meteorological, pollutant, and IHD hospitalization data from Xining and Xinxiang from 2016 to 2021. Using a time-stratified case-crossover approach, we fitted conditional Poisson regression models to assess the association between cold waves, PM 2.5 , and IHD hospitalizations and quantified their interactions. Additionally, we calculated the attributable fraction (AF) and attributable number (AN) of hospitalizations due to exposure to cold waves and medium to high-level PM 2.5 . We also performed stratified analyses by altitude, gender, and age. Both cold waves and PM 2.5 were positively associated with IHD hospitalization rates in Xining and Xinxiang, but the differences between the two regions were not significant. The relative risk of cold waves was 1.15 (1.07, 1.24) in Xining and 1.16 (1.11, 1.21) in Xinxiang. In Xining, there was an interaction between cold waves and different levels of PM 2.5 . We estimated the attributable fraction due to the joint exposure of cold waves and PM 2.5 to be 0.14-0.49 in Xining and 0.26-0.36 in Xinxiang. Older adults and males faced higher risks. This study highlights the importance of reducing PM 2.5 exposure and optimizing extreme weather warning systems and suggests further exploration of the impacts of individual behaviors and regional characteristics on IHD.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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