Cardiac-Sympathetic Contractility and Neural Alpha-Band Power: Cross-Modal Collaboration during Approach-Avoidance Conflict.

Autor:	Dundon NM; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106 neil.dundon@psych.ucsb.edu.; Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University of Freiburg, Freiburg 79104, Germany., Stuber A; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106., Bullock T; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106., Garcia JO; Humans in Complex Systems Division, US DEVCOM Army Research Laboratory, Aberdeen Proving Ground, Maryland 21005., Babenko V; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106.; BIOPAC Systems Inc., Goleta, California 93117., Rizor E; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106.; Interdepartmental Graduate Program in Dynamical Neuroscience, University of California, Santa Barbara, California 93106., Yang D; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106.; Department of Computer Science, University of California, Santa Barbara, California 93106., Giesbrecht B; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.; Institute for Collaborative Biotechnologies, University of California, Santa Barbara, California 93106.; Interdepartmental Graduate Program in Dynamical Neuroscience, University of California, Santa Barbara, California 93106., Grafton ST; Department of Psychological & Brain Sciences, University of California, Santa Barbara, California 93106.
Jazyk:	angličtina
Zdroj:	The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Oct 09; Vol. 44 (41). Date of Electronic Publication: 2024 Oct 09.
DOI:	10.1523/JNEUROSCI.2008-23.2024
Abstrakt:	As evidence mounts that the cardiac-sympathetic nervous system reacts to challenging cognitive settings, we ask if these responses are epiphenomenal companions or if there is evidence suggesting a more intertwined role of this system with cognitive function. Healthy male and female human participants performed an approach-avoidance paradigm, trading off monetary reward for painful electric shock, while we recorded simultaneous electroencephalographic and cardiac-sympathetic signals. Participants were reward sensitive but also experienced approach-avoidance "conflict" when the subjective appeal of the reward was near equivalent to the revulsion of the cost. Drift-diffusion model parameters suggested that participants managed conflict in part by integrating larger volumes of evidence into choices (wider decision boundaries). Late alpha-band (neural) dynamics were consistent with widening decision boundaries serving to combat reward sensitivity and spread attention more fairly to all dimensions of available information. Independently, wider boundaries were also associated with cardiac "contractility" (an index of sympathetically mediated positive inotropy). We also saw evidence of conflict-specific "collaboration" between the neural and cardiac-sympathetic signals. In states of high conflict, the alignment (i.e., product) of alpha dynamics and contractility were associated with a further widening of the boundary, independent of either signal's singular association. Cross-trial coherence analyses provided additional evidence that the autonomic systems controlling cardiac-sympathetics might influence the assessment of information streams during conflict by disrupting or overriding reward processing. We conclude that cardiac-sympathetic control might play a critical role, in collaboration with cognitive processes, during the approach-avoidance conflict in humans. Competing Interests: The authors declare no competing financial interests. (Copyright © 2024 the authors.)
Databáze:	MEDLINE
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