Involvement of cognitive abilities in the occurrence of fractures in fallers aged 55 years or older: a cross-sectional study.

Autor: Attoh-Mensah E; Normandie Univ, UNICAEN, INSERM, COMETE, CYCERON, Caen, 14000, France. kouakou.attoh-mensah@unilim.fr.; Permanent address: Univ. Limoges, HAVAE, 123 Avenue Albert Thomas, UR, 20217, F-87000, Limoges, Limoges, France. kouakou.attoh-mensah@unilim.fr., Pothier K; Department of Psychology, PAVeA Laboratory (UR 2114), University of Tours, Tours, 37000, France., Loggia G; Normandie Univ, UNICAEN, INSERM, COMETE, CYCERON, Caen, 14000, France.; Department of Geriatrics, Normandie Univ, UNICAEN, CHU de Caen, Caen, 14000, France., Morello R; Department of Statistics and Clinical Research, Normandie Univ, UNICAEN, CHU de Caen, Caen, 14000, France., Chavoix C; Normandie Univ, UNICAEN, INSERM, COMETE, CYCERON, Caen, 14000, France., Marcelli C; Normandie Univ, UNICAEN, INSERM, COMETE, CYCERON, Caen, 14000, France.; Department of Rheumatology, Normandie Univ, CHU de Caen, Caen, 14000, France.
Jazyk: angličtina
Zdroj: Aging clinical and experimental research [Aging Clin Exp Res] 2024 Aug 30; Vol. 36 (1), pp. 180. Date of Electronic Publication: 2024 Aug 30.
DOI: 10.1007/s40520-024-02830-7
Abstrakt: Background: Both bone fragility and poor cognitive functions are known to contribute to fracture occurrence, but it remains unclear whether their contribution is independent of each other and which cognitive dysfunctions are most involved. This study aimed to clarify the involvement of various cognitive abilities in fall-related fractures among community-dwelling fallers aged 55 and over, and to determine whether poor cognitive abilities is a risk factor independent of bone fragility.
Methods: In a cross-sectional study, we collected sociodemographic and medical data, including bone mineral density (BMD), and performed cognitive and mobility assessments in 189 individuals with a history of fall in the previous year.
Results: Fallers with a fracture had poorer cognitive and mobility performance than non-injured fallers. Multivariate regressions revealed that cognition, BMD and other risk factors were independently associated with fracture among all participants (OR = 1.04, 95% CI = 1.01-1.08, p = 0.034 for completion time on part A of the Trail Making Test [TMT-A], and OR = 0.53, 95% CI = 0.33-0.84, p < 0.001 for BMD), particularly in women (OR = 0.77, 95% CI = 0.60-0.98, p = 0.039 for backward digit span score, and OR = 0.43, 95% CI = 0.25-0.75, p = 0.001 for BMD).
Conclusion: Thus, poor cognition, especially poor processing speed and working memory, is associated with an increased risk of fracture in fallers, particularly in women, regardless of BMD or other fracture risk factors. Hence, an in-depth cognitive evaluation should enhance the detection of fallers at risk of fracture, particularly in the absence of signs of osteoporosis, and thus ensure the best possible prevention.
(© 2024. The Author(s).)
Databáze: MEDLINE
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