Retinal Toxicity Assessment Following Vitreoretinal Surgery: A Comparison of Silicone Oil and Perfluoropropane Tamponade Using Diopsys ® NOVA ™ .

Autor: Ozal SA; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Karapapak M; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Ozal E; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Ermis S; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Guler S; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Baybora H; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Ciloglu Hayat S; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey., Yılmaz YC; Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, University of Health Science, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Current eye research [Curr Eye Res] 2024 Aug 30, pp. 1-6. Date of Electronic Publication: 2024 Aug 30.
DOI: 10.1080/02713683.2024.2394118
Abstrakt: Purpose: This study aimed to assess and compare the retinal toxicity associated with silicone oil (SO) and perfluoropropane (C3F8) tamponade following vitreoretinal surgery for fresh rhegmatogenous retinal detachment (RRD), utilizing the office-based Diopsys ® NOVA system for evaluation.
Methods: Patients who underwent vitreoretinal surgery for fresh RRD and had SO (group 1) or C3F8 (group 2) tamponade were included in a prospective analysis. Flicker full field electroretinography (ffERG) and pattern electroretinography (PERG) tests were performed at 6 months postoperatively.
Results: Postoperative best corrected visual acuity (logMAR) was significantly different in group 1 and group 2 patients, 0.48 ± 0.3 and 0.30 ± 0.2, respectively. No significant disparities were found in demographic variables. Flicker ffERG and PERG recordings revealed notable alterations in retinal function parameters in the group 1 compared to the group 2.
Conclusion: Our findings suggest a correlation between SO tamponade and retinal dysfunction, evidenced by office-based ERG measurements. The Diopsys ® NOVA protocol offers clinical ease in assessing retinal function. Further controlled studies are essential to validate these findings and guide clinical practice effectively.
Databáze: MEDLINE