Associations between type 2 diabetes mellitus and risk of falls among community-dwelling elderly people in Guangzhou, China: a prospective cohort study.

Autor: Lin WQ; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China.; Institute of Public Health, Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention, Guangzhou, 510440, China., Liao YX; School of Public Health, Guangzhou Medical University, Guangzhou, 511436, China., Wang JY; Institute of Applied Health Research, University of Birmingham, Birmingham, B152TT, UK., Luo LY; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Yuan LX; Brain Hospital of Guangzhou Medical University, Guangzhou Huiai Hospital, Guangzhou, 510370, China., Sun SY; School of Public Health, Southern Medical University, Guangzhou, 510515, China., Xu Y; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Sun MY; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Wang C; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Zhou Q; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Liu XY; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China., Liu H; Department of Basic Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou, 510440, China. gzcdc_liuhui@163.com.
Jazyk: angličtina
Zdroj: BMC geriatrics [BMC Geriatr] 2024 Aug 29; Vol. 24 (1), pp. 717. Date of Electronic Publication: 2024 Aug 29.
DOI: 10.1186/s12877-024-05314-5
Abstrakt: Background: Several studies have demonstrated that older adults with type 2 diabetes mellitus (T2DM) have a higher risk of falls compared to those without T2DM, which may lead to disability and a lower quality of life. While, limited prospective studies have quantified the associations in southern China. We conducted a longitudinal cohort study to quantify the associations between T2DM and falls and investigate the risk factors of falls among community-dwelling elderly people in Guangzhou, China.
Methods: The population-based study included 8800 residents aged 65 and over in 11 counties of Guangzhou at baseline in 2020 and then prospectively followed up through 2022. Of 6169 participants had complete follow-up and were included in the present study. A fall event was identified by self-reported. The Cox regression was applied to quantify the associations between T2DM and falls, and hazard ratios (HRs) were calculated to the factors associated with falls among participants.
Results: The median follow-up time for participants was 2.42 years. During the follow-up period, the incidence of falls among all participants was 21.96%. After adjusting for covariates in Cox regression models, T2DM remained a significant risk factor for falls, with HR of 1.781 (95% CI: 1.600-1.983) in the unadjusted covariates model and 1.757 (1.577-1.957) in the adjusted covariates model. Female (1.286, 1.136-1.457), older age (≥ 80: 1.448, 1.214-1.729), single marital status (1.239, 1.039-1.477), lower education level (primary school and below: 1.619, 1.004-1.361), hypertension (1.149, 1.026-1.286) and stroke (1.619, 1.176-2.228) were associated with a higher risk of falls, whereas everyday physical exercise (0.793, 0.686-0.918) was associated with a lower risk of falls.
Conclusion: Falls are common, with risks between T2DM and falls quantified and several factors investigated in the longitudinal cohort study among community-dwelling elderly people in Guangzhou, China. Targeted action on the risk factors may reduce the burden of falls in elderly people with T2DM in the future.
(© 2024. The Author(s).)
Databáze: MEDLINE
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