A prospective histopathological analysis of the inferior turbinate: which functional parts should be preserved during turbinate surgery?

Autor:	AlSharhan SS; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Otorhinolaryngology, Dammam, Saudi Arabia. Electronic address: ssalsharhan@iau.edu.sa., AlNafea NM; King Faisal Specialist Hospital and Research Center, Department of Otorhinolaryngology, Riyadh, Saudi Arabia., Ashoor MM; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Otorhinolaryngology, Dammam, Saudi Arabia., AlMarzouq WF; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Otorhinolaryngology, Dammam, Saudi Arabia., AlHumaid SA; King Abdulaziz Medical City, National Guard Health Affairs, Department of Otorhinolaryngology, Jeddah, Saudi Arabia., ALBahrani NA; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Otorhinolaryngology, Dammam, Saudi Arabia., Nemer AMA; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Pathology, Dammam, Saudi Arabia., AlOmar RS; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Family and Community Medicine, Dammam, Saudi Arabia., Aljubran HJ; Imam Abdulrahman Bin Faisal University, College of Medicine, Department of Otorhinolaryngology, Dammam, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Brazilian journal of otorhinolaryngology [Braz J Otorhinolaryngol] 2024 Nov-Dec; Vol. 90 (6), pp. 101486. Date of Electronic Publication: 2024 Aug 09.
DOI:	10.1016/j.bjorl.2024.101486
Abstrakt:	Objective: Inferior turbinate (IT) hypertrophy-induced chronic nasal obstruction is one of the most common problems in rhinology. However, the histopathological analysis of the hypertrophic IT is unclear. Therefore, this study aimed to identify the histological changes and the most functional areas of the IT to assist otolaryngologists with improving and modifying surgical techniques and minimizing potential complications. Methods: This prospective, cross-sectional study was conducted to evaluate the contribution of hypertrophic IT to nasal obstruction. For the analysis, a total of 38 adult patients (IT hypertrophy group and non-IT hypertrophy [control] group) were enrolled, and 131 specimens were obtained during the surgical procedures (IT hypertrophy group, endoscopic submucosal turbinoplasty and septoplasty; non-IT hypertrophy group, septoplasty). Intraoperative samples were collected from four sites of the IT to determine the dimensions, composition, and possible pathological changes in each individual site. The samples were analyzed using light microscopy. Results: A comparison of the four sites of the IT in the IT hypertrophy group showed that the posterior end had the highest normal epithelium percentage, and cilia count. This suggests that preserving the functional part of the IT during surgery is crucial. Furthermore, a comparison of both groups in terms of basement membrane thickness and vessel wall thickness (p = 0.005 and p = 0.03, respectively) showed significant differences. Conclusion: Our findings can assist otolaryngologists select the most appropriate surgical procedures for IT hypertrophy. In addition, they advocate the importance of preserving the functional part of the IT during surgical intervention to achieve an efficiently working IT and avoid undesirable complications while improving the nasal airway passage. Level of Evidence: Level 3. (Copyright © 2024 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier España S.L.U. All rights reserved.)
Databáze:	MEDLINE
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