Sample tilting for speckle suppression through angular compounding.

Autor: Rao Chintada B, Keahey P, Uribe-Patarroyo N, Bouma BE, Villiger M
Jazyk: angličtina
Zdroj: Optics letters [Opt Lett] 2024 Sep 01; Vol. 49 (17), pp. 4979-4982.
DOI: 10.1364/OL.533271
Abstrakt: Speckle degrades the quality of optical coherence tomography (OCT) images and impedes their visual interpretation. Current hardware methods for speckle suppression necessitate difficult hardware modifications. As a result, algorithmic approaches for speckle suppression generally lack validation or training with physically meaningful ground truth. Here, we demonstrate angular compounding through tilting of the sample with a motorized rotation stage. Tomograms acquired at different tilt angles are related to each other through a physics-informed affine map, which can be retrieved directly from the measurement data. Using a mechanical sample tilting stage obviates the need to alter the OCT hardware and enables effective angular compounding with existing OCT instruments.
Databáze: MEDLINE