Is Vitamin D a Crucial Molecule for Musculoskeletal and Cardiovascular Systems in Postmenopausal Women?
| Autor: | Korkmaz H; Department of Physiology, Faculty of Medicine, Hacettepe University, 06230 Ankara, Turkey., Pehlivanoğlu B; Department of Physiology, Faculty of Medicine, Hacettepe University, 06230 Ankara, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2024 Aug 15; Vol. 29 (8), pp. 281. |
| DOI: | 10.31083/j.fbl2908281 |
| Abstrakt: | Vitamin D, a steroid hormone, acts via the vitamin D receptor expressed in various tissues, including bones, muscles, and the cardiovascular system and is associated with well-being of individuals and vitamin D deficiency is considered as a prevalent public health problem. Menopause is an important cornerstone for women, where the hormonal changes may lead to adverse health effects. Vitamin D deficiency during menopausal transition or in postmenopausal period may aggravate the health risks such as osteoporosis, sarcopenia, and cardiovascular diseases associated with menopause. This manuscript aims to provide a review of the complex interaction between vitamin D deficiency and the well-being of postmenopausal women, focusing on musculoskeletal and cardiovascular implications. Clinical studies highlight the importance of maintaining optimal vitamin D levels to decrease the risk of musculoskeletal disorders and cardiovascular diseases in postmenopausal women. However, conflicting findings regarding the effectiveness of vitamin D supplementation in reducing cardiovascular risk suggest the need for further research and a personalized approach for the chemical form of Vitamin D, dose, duration of deficiency, individual variations, and accompanying conditions. The use of vitamin D supplementation in well-evaluated patients is desirable, and help to optimize health status in postmenopausal women. Competing Interests: The authors declare no conflict of interest. (© 2024 The Author(s). Published by IMR Press.) |
| Databáze: | MEDLINE |
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