How Flow Diverter Selection Can Affect the Flow Changes within a Jailed Ophthalmic Artery: A Computational Fluid Dynamics Study.

Autor: Ünsal C; Numerical Simulation and Spray Targeting Division, Department of Engineering, Bosch, Bursa, Türkiye., Güçlü G; Department of Mechanical Engineering, Southern Methodist University, Dallas, Texas, United States., Olcay AB; Department of Mechanical Engineering, Faculty of Engineering, Yeditepe University, Istanbul, Türkiye., Hassankhani A; Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States., Bilgin C; Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States., Hakyemez B; Department of Radiology, Uludag University School of Medicine, Bursa, Türkiye.
Jazyk: angličtina
Zdroj: Asian journal of neurosurgery [Asian J Neurosurg] 2024 Jun 27; Vol. 19 (3), pp. 426-434. Date of Electronic Publication: 2024 Jun 27 (Print Publication: 2024).
DOI: 10.1055/s-0044-1787868
Abstrakt: Introduction  Flow diverter (FD) stents are widely used to treat giant aneurysms by reducing blood flow into the aneurysm sac. However, choosing the optimal FD for a patient can be challenging when a nearby artery, such as the ophthalmic artery (OA), is jailed by the FD placement. This study compares the impact of two FD stents with different effective metal surface area (EMSA) values on OA occlusion. Materials and Methods  A numerical model of a 59-year-old female patient with a giant aneurysm in the left internal carotid artery and a jailed OA was created based on clinical data. Two FD stents, FRED4017 and FRED4518, with different EMSA values at the aneurysm neck and OA inlet, were virtually deployed in the model. Blood flow and occlusion amount in the OA were simulated and compared between the two FD stents. Results  FRED4017 had higher EMSA values than FRED4518 at the aneurysm neck (35% vs. 24.6%) and lower EMSA values at the OA inlet (15% vs. 21.2%). FRED4017 caused more occlusion in the OA than FRED4518 (40% vs. 28%), indicating a higher risk of ocular ischemic syndrome. Conclusion  The EMSA value of FD stents affects the blood flow and occlusion amount in the jailed OA. Therefore, selecting an FD stent with a low EMSA value at the OA inlet may be beneficial for patients with a nearby jailed artery at the aneurysm neck.
Competing Interests: Conflict of Interest None declared.
(Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje