Autor: |
Liberati C; Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy., Sturniolo G; Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy., Brigadoi G; Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy., Cavinato S; Infectious and Tropical Diseases Unit, Padua University Hospital, 35126 Padua, Italy., Visentin S; Department of Women's and Children's Health, Gynecological and Obstetric Clinic, Padua University Hospital, 35126 Padua, Italy., Cosmi E; Department of Women's and Children's Health, Gynecological and Obstetric Clinic, Padua University Hospital, 35126 Padua, Italy., Donà D; Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy., Rampon O; Department of Women's and Children's Health, Pediatric Infectious Disease, Padua University Hospital, 35126 Padua, Italy. |
Abstrakt: |
Cytomegalovirus causes the most common congenital infection worldwide. With most infants asymptomatic at birth, the few affected may present with variable clinical scenarios, from isolated hearing loss to severe neurologic impairment. Public health interventions include all actions at the health system, community, and individual levels that aim at reducing the burden of congenital Cytomegalovirus. This review examines the literature on maternal and neonatal screening programs in light of current evidence for treatment and the development of vaccines against Cytomegalovirus. Potential biases and benefits of these interventions are outlined, with the objective of increasing awareness about the problem and providing readers with data and critical tools to participate in this ongoing debate. |