Exploring the Feasibility of Bidirectional Control of Beta Oscillatory Power in Healthy Controls as a Potential Intervention for Parkinson's Disease Movement Impairment.

Autor: Anil K; School of Health Professions, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK.; Brain Research and Imaging Centre, Faculty of Health, University of Plymouth, Research Way, Plymouth PL6 8BU, UK., Ganis G; Brain Research and Imaging Centre, Faculty of Health, University of Plymouth, Research Way, Plymouth PL6 8BU, UK.; School of Psychology, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK., Freeman JA; Peninsula Allied Health Centre, School of Health Professions, University of Plymouth, Derriford Road, Plymouth PL6 8BH, UK., Marsden J; School of Health Professions, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK.; Brain Research and Imaging Centre, Faculty of Health, University of Plymouth, Research Way, Plymouth PL6 8BU, UK., Hall SD; Brain Research and Imaging Centre, Faculty of Health, University of Plymouth, Research Way, Plymouth PL6 8BU, UK.; School of Psychology, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK.
Jazyk: angličtina
Zdroj: Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Aug 06; Vol. 24 (16). Date of Electronic Publication: 2024 Aug 06.
DOI: 10.3390/s24165107
Abstrakt: Neurofeedback (NF) is a promising intervention for improvements in motor performance in Parkinson's disease. This NF pilot study in healthy participants aimed to achieve the following: (1) determine participants' ability to bi-directionally modulate sensorimotor beta power and (2) determine the effect of NF on movement performance. A real-time EEG-NF protocol was used to train participants to increase and decrease their individual motor cortex beta power amplitude, using a within-subject double-blind sham-controlled approach. Movement was assessed using a Go/No-go task. Participants completed the NASA Task Load Index and provided verbal feedback of the NF task difficulty. All 17 participants (median age = 38 (19-65); 10 females) reliably reduced sensorimotor beta power. No participant could reliably increase their beta activity. Participants reported that the NF task was challenging, particularly increasing beta. A modest but significant increase in reaction time correlated with a reduction in beta power only in the real condition. Findings suggest that beta power control difficulty varies by modulation direction, affecting participant perceptions. A correlation between beta power reduction and reaction times only in the real condition suggests that intentional beta power reduction may shorten reaction times. Future research should examine the minimum beta threshold for meaningful motor improvements, and the relationship between EEG mechanisms and NF learning to optimise NF outcomes.
Databáze: MEDLINE
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