| Autor: |
Yıldırım M; Department of Biochemistry, Faculty of Pharmacy, Harran University, Sanliurfa 63050, Türkiye., Erşatır M; Department of Chemistry, Faculty of Art and Science, Cukurova University, Adana 01330, Türkiye., Poyraz S; Independent Researcher, Nevşehir 50040, Türkiye., Amangeldinova M; Department of Biodiversity and Biological Resources, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Av., 71, Almaty 050040, Kazakhstan.; Institute of Genetic and Physiology, Al-Farabi Av., 93, Almaty 050040, Kazakhstan., Kudrina NO; Department of Biodiversity and Biological Resources, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Av., 71, Almaty 050040, Kazakhstan.; Institute of Genetic and Physiology, Al-Farabi Av., 93, Almaty 050040, Kazakhstan., Terletskaya NV; Department of Biodiversity and Biological Resources, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Av., 71, Almaty 050040, Kazakhstan.; Institute of Genetic and Physiology, Al-Farabi Av., 93, Almaty 050040, Kazakhstan. |
| Abstrakt: |
In recent years, the supercritical CO 2 extraction method has gained attention due to its use of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that do not cause the degradation of bioactive compounds, and capacity for rapid extraction. This method is particularly notable for isolating bioactive compounds from plants. The extracts obtained have shown superior properties due to their activity against diseases such as cancer, which is one of the leading causes of death worldwide. The aim of this study is to provide an in-depth understanding of the supercritical CO 2 extraction method, as well as to discuss its advantages and disadvantages. Furthermore, the study includes specific data on various plant materials, detailing the following parameters: plant name and region, bioactive compounds or compound classes, extraction temperature (°C), pressure (bar), time (minutes), co-solvent used, and flow rate. Additionally, this study covers extensive research on the isolation of bioactive compounds and the efficacy of the obtained extracts against cancer. |
