Cancer and the Microbiome of the Human Body.

Autor: Herrera-Quintana L; Department of Physiology, Schools of Pharmacy and Medicine, University of Granada, 18071 Granada, Spain.; Biomedical Research Center, Health Sciences Technology Park, University of Granada, 18016 Granada, Spain., Vázquez-Lorente H; Department of Physiology, Schools of Pharmacy and Medicine, University of Granada, 18071 Granada, Spain.; Biomedical Research Center, Health Sciences Technology Park, University of Granada, 18016 Granada, Spain., Lopez-Garzon M; Biomedical Group (BIO277), Department of Physical Therapy, Health Sciences Faculty, University of Granada, 18171 Granada, Spain., Cortés-Martín A; PROmoting FITness and Health through Physical Activity Research Group (PROFITH), Sport and Health University Research Institute (iMUDS), University of Granada, 18016 Granada, Spain.; APC Microbiome Ireland, School of Microbiology, University College Cork, T12 YT20 Cork, Ireland., Plaza-Diaz J; Department of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Campus de Cartuja s/n, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria IBS.GRANADA, Complejo Hospitalario Universitario de Granada, 18014 Granada, Spain.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1, Canada.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2024 Aug 21; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 21.
DOI: 10.3390/nu16162790
Abstrakt: Cancer remains a public health concern worldwide, with its incidence increasing worldwide and expected to continue growing during the next decades. The microbiome has emerged as a central factor in human health and disease, demonstrating an intricate relationship between the microbiome and cancer. Although some microbiomes present within local tissues have been shown to restrict cancer development, mainly by interacting with cancer cells or the host immune system, some microorganisms are harmful to human health and risk factors for cancer development. This review summarizes the recent evidence concerning the microbiome and some of the most common cancer types (i.e., lung, head and neck, breast, gastric, colorectal, prostate, and cervix cancers), providing a general overview of future clinical approaches and perspectives.
Databáze: MEDLINE