Resilience in Adult Coeliac Patients on a Gluten-Free Diet: A Cross-Sectional Multicentre Italian Study.

Autor:	Schiepatti A; Department of Internal Medicine and Therapeutics, University of Pavia, Italy, 27100 Pavia, Italy.; Gastroenterology Unit of Pavia Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy., Maimaris S; Department of Internal Medicine and Therapeutics, University of Pavia, Italy, 27100 Pavia, Italy.; Gastroenterology Unit of Pavia Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy., Randazzo S; Department of Internal Medicine and Therapeutics, University of Pavia, Italy, 27100 Pavia, Italy., Maniero D; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padua, Italy., Biti R; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padua, Italy., Caio G; Department of Translational Medicine, St. Anna Hospital, University of Ferrara, 44121 Ferrara, Italy.; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital-Harvard Medical School, Boston, MA 02114, USA., Lungaro L; Department of Translational Medicine, St. Anna Hospital, University of Ferrara, 44121 Ferrara, Italy., Carroccio A; Unit of Internal Medicine, 'V. Cervello' Hospital, Ospedali Riuniti 'Villa Sofia-Cervello', 90146 Palermo, Italy.; Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy., Seidita A; Unit of Internal Medicine, 'V. Cervello' Hospital, Ospedali Riuniti 'Villa Sofia-Cervello', 90146 Palermo, Italy.; Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.; Institute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), 90146 Palermo, Italy., Scalvini D; Department of Internal Medicine and Therapeutics, University of Pavia, Italy, 27100 Pavia, Italy.; Gastroenterology Unit of Pavia Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy., Ciacci C; Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84081 Salerno, Italy., Biagi F; Department of Internal Medicine and Therapeutics, University of Pavia, Italy, 27100 Pavia, Italy.; Gastroenterology Unit of Pavia Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27100 Pavia, Italy., Zingone F; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35128 Padua, Italy.; Unit of Gastroenterology, Azienda Ospedale Università Padova, 35128 Padova, Italy.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2024 Aug 07; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 07.
DOI:	10.3390/nu16162595
Abstrakt:	Background: Data on resilience, the ability to recover from adversity, in coeliac disease (CeD) are lacking. Aim: To assess the degree of resilience in patients with CeD on a gluten-free diet (GFD), and its association with clinical features, sociodemographic factors, psychological morbidity, and quality of life (QOL). Methods: A cross-sectional multicentre Italian study was conducted on adult CeD patients between May 2022 and April 2023. Connor-Davidson Resilience Scale (CD-RISC), the Coeliac Disease-specific Quality of Life Scale (CD-QOL), the State-Trait Anxiety Inventory scale (STAI-Y), and the Beck Depression Inventory scale (BDI) were used to evaluate resilience, QOL, anxiety, and depression, respectively. A multivariate analysis was conducted to identify factors independently associated with the degree of resilience. Results: A total of 305 patients (221 F, mean age at CeD diagnosis 36 ± 16 years) on a long-term GFD (median 8 years, IQR 3-17) were enrolled. A total of 298/305 patients (98%) had a high level of resilience (CD-RISC ≥ 35). At univariate analysis, resilience was statistically associated with male gender ( p = 0.03), age at enrolment ( p = 0.02), marital status ( p = 0.03), QOL ( p < 0.001), anxiety ( p < 0.001), and depression ( p < 0.001). On multivariate regression analysis, trait anxiety (STAI-Y2, p < 0.001) and depression (BDI, p = 0.02) were independent predictors of lower levels of resilience. Conclusions: Higher trait anxiety predicts lower levels of resilience. Targeted interventions in this subgroup of patients may be helpful for their management and follow-up.
Databáze:	MEDLINE
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