| Autor: |
Medici A; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy., De Nisco M; Department of Sciences, University of Basilicata, Viale dell'Ateneo Lucano, 85100 Potenza, Italy., Luongo G; Associazione Italiana per la Promozione delle Ricerche su Ambiente e Salute Umana, 82030 Dugenta, Italy., Di Fabio G; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy., Brigante M; Institut de Chimie de Clermont-Ferrand, Université Clermont Auvergne, CNRS, Clermont Auvergne INP, F-63000 Clermont-Ferrand, France., Zarrelli A; Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy. |
| Jazyk: |
angličtina |
| Zdroj: |
Molecules (Basel, Switzerland) [Molecules] 2024 Aug 09; Vol. 29 (16). Date of Electronic Publication: 2024 Aug 09. |
| DOI: |
10.3390/molecules29163783 |
| Abstrakt: |
In recent years, the environmental impact of pharmaceutical residues has emerged as a pressing global concern, catalyzed by their widespread usage and persistence in aquatic ecosystems. Among these pharmaceuticals, acyclovir (ACV) stands out due to its extensive prescription during medical treatments for herpes simplex virus, chickenpox, and shingles, as well as its heightened usage amidst the COVID-19 pandemic. ACV is excreted largely unchanged by the human body, leading to significant environmental release through wastewater effluents. The urgency of addressing ACV's environmental impact lies in its potential to persist in water bodies and affect aquatic life. This persistence underscores the critical need for effective degradation strategies that can mitigate its presence in aquatic systems. This study focuses on employing sodium hypochlorite as an oxidative agent for the degradation of ACV, leveraging its common use in wastewater treatment plants. Our research aims to explore the kinetics of ACV degradation, identify and characterize its degradation byproducts, and optimize the conditions under which complete degradation can be achieved. By assessing the efficiency of sodium hypochlorite in real wastewater samples, this study seeks to provide practical insights into mitigating ACV contamination in aquatic environments. The novelty of this research lies in its comprehensive approach to understanding the degradation pathways of ACV and evaluating the feasibility of using sodium hypochlorite as a sustainable solution in wastewater treatment. By addressing the environmental concerns associated with ACV and offering practical solutions, this study contributes to the broader goal of sustainable pharmaceutical waste management and environmental stewardship. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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