Autor: |
Turcu TA; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Pediatric Poison Centre, 'Grigore Alexandrescu' Clinical Emergency Hospital for Children, 017443 Bucharest, Romania., Lescaie A; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Pediatric Poison Centre, 'Grigore Alexandrescu' Clinical Emergency Hospital for Children, 017443 Bucharest, Romania., Grama AR; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Pediatric Poison Centre, 'Grigore Alexandrescu' Clinical Emergency Hospital for Children, 017443 Bucharest, Romania., Strătulă AC; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Vincene AI; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Grigoraș LM; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Jităreanu C; Pediatric Poison Centre, 'Saint Mary' Clinical Emergency Hospital for Children, 700309 Iași, Romania.; Department of Pediatrics, Apollonia University, 700511 Iași, Romania., Babeu AM; Emergency Department, 'Louis Turcanu' Clinical Emergency Hospital for Children, 300011 Timișoara, Romania., Gafencu M; Pediatric Poison Centre, 'Louis Turcanu' Clinical Emergency Hospital for Children, 300011 Timișoara, Romania.; Department of Pediatrics, 'Victor Babeș' University of Medicine and Pharmacy, 300041 Timișoara, Romania., Crăciun MD; Department of Epidemiology, 'Carol Davila' University of Medicine and Pharmacy, 010221 Bucharest, Romania.; Department of Infection Prevention and Control, Grigore Alexandrescu Clinical Emergency Hospital for Children, 011743 Bucharest, Romania., Chivu CD; Department of Epidemiology, 'Carol Davila' University of Medicine and Pharmacy, 010221 Bucharest, Romania.; Department of Infection Prevention and Control, Grigore Alexandrescu Clinical Emergency Hospital for Children, 011743 Bucharest, Romania., Baconi DL; Department of Toxicology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania., Mihai CM; Department of Pediatrics, 'Ovidius' University of Medicine and Pharmacy, 900470 Constanta, Romania.; Pediatric Poison Center, County Clinical Emergency Hospital of Constanta, 900470 Constanta, Romania., Ulmeanu CE; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Pediatric Poison Centre, 'Grigore Alexandrescu' Clinical Emergency Hospital for Children, 017443 Bucharest, Romania., Nițescu GV; Department of Pediatrics, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.; Pediatric Poison Centre, 'Grigore Alexandrescu' Clinical Emergency Hospital for Children, 017443 Bucharest, Romania. |
Abstrakt: |
This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns in substance use. Data from 562 adolescents were collected from three paediatric poison centres in Romania between January 2017 and December 2022. This study analysed the epidemiological and sociodemographic characteristics of the adolescents, including age, gender, place of residence, history of substance abuse, psychiatric history, and history of institutionalised care. The findings revealed that cannabis and new psychoactive substances (NPSs) are the most commonly implicated substances, each with distinct profiles among adolescents. Cannabis was involved in 46.1% of cases, with a significant association with urban residency. NPSs were identified as the second most prevalent substance, accounting for 39.3% of cases. These were more prevalent in rural areas and among patients with psychiatric disorders. Cannabis and NPSs were also the most commonly implicated substances in acute intentional poisoning cases with substances of abuse. These substances have distinct profiles among adolescents, including age, gender, residency area, history of substance abuse, psychiatric history, and institutional care. These findings underscore the necessity of targeted public health interventions and integrated care approaches to address substance use and related mental health issues in adolescents. |