| Autor: |
Li J; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Kudereti T; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Wusiman A; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Abula S; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., He X; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Li J; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Yang Y; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Guo Q; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China., Guo Q; College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.; Xinjiang Key Laboratory of New Drug Study and Creation for Herbivorous Animals, Urumqi 830052, China. |
| Abstrakt: |
The present study was designed to assess the impact of Alhagi honey small-molecule sugars (AHAS) on Hu lambs. Therefore, in this study, AHAS low-dose (AHAS-L, 200 mg/ kg per day), AHAS medium-dose (AHAS-M, 400 mg/kg per day), and AHAS high-dose (AHAS-H, 800 mg/kg per day) were administered to Hu lambs to investigate the regulatory effects of AHAS on growth performance, oxidation index, immune system enhancement, and intestinal microbiota. The results showed that lambs in the AHAS-H group exhibited significantly increased in average daily weight gain, and growth performance compared to those in the control group ( p < 0.05). Moreover, AHAS-H supplementation resulted in increased levels of serum antioxidant enzymes (SOD, GSH-Px, and T-AOC), serum antibodies (IgA, IgG, and IgM), and cytokines (IL-4, 10,17, IFN-γ, and TNF-α) compared with the control group ( p < 0.05). Additionally, it increased the quantity and richness of beneficial bacteria at such as Sphingomonas , Ralstonia , and Flavobacterium , activating various metabolic pathways and promoting the production of various short-chain fatty acids. In summary, our findings highlight the potential of AHAS-H treatment in enhancing intestinal health of lambs by improving intestinal function, immunity, and related metabolic pathways. Consequently, these results suggest that AHAS holds promising potential as a valuable intervention for optimizing growth performance and intestinal health in lambs. |
