Racial disparities in trend, clinical characteristics and outcomes in Takotsubo syndrome.

Autor: Ang SP; Department of Internal Medicine, Rutgers Health/Community Medical Center, Toms River, NJ, USA. Electronic address: spa45@rutgers.edu., Chia JE; Department of Internal Medicine, Texas Tech University Health Science Center, El Paso, TX, USA., Krittanawong C; Cardiology Division, NYU Langone Health and NYU School of Medicine, New York, NY, USA., Vummadi T; Department of Anesthesiology, University of Central Florida, Ocala, FL, USA., Deshmukh A; Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA., Usman MH; Department of Cardiovascular Disease, Newark Beth Israel Medical Center, Newark, NJ, USA., Lavie CJ; Department of Cardiovascular Disease, John Ochsner Heart and Vascular Institute, New Orleans, LA, USA. Electronic address: clavie@ochsner.org., Mukherjee D; Department of Internal Medicine, Texas Tech University Health Science Center, El Paso, TX, USA; Department of Cardiovascular Medicine, Texas Tech University Health Science Center, El Paso, TX, USA.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Nov; Vol. 49 (11), pp. 102826. Date of Electronic Publication: 2024 Aug 27.
DOI: 10.1016/j.cpcardiol.2024.102826
Abstrakt: Introduction: Takotsubo syndrome (TTS) is an acute transient nonischemic cardiomyopathy often characterized by its hallmark feature of left ventricular apical ballooning. The correlation between racial backgrounds and the prognosis of individuals with TTS remains poorly defined. Our study aimed to explore the influence of race on the trends, clinical presentations, and outcomes in patients diagnosed with TTS.
Methods: We queried the National Inpatient Sample (NIS) database from 2016 to 2020 and identified hospitalizations with TTS. We compared the clinical features and outcomes across three different races - non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic population. The primary outcome was in-hospital mortality.
Results: 76,505 weighted hospitalizations for TTS were identified, of which 65,495 (85.6%) were non-Hispanic White, 5,830 (7.6%) were non-Hispanic Black, and 5,180 (6.8%) were Hispanics. After propensity-score matching, NHB patients had higher odds of acute kidney injury (OR: 1.49, 95% CI: 1.21-1.84, p < 0.001) and mechanical ventilation (OR: 1.33, 95% CI: 1.04-1.68, p = 0.02). Hispanic patients had a higher incidence of acute kidney injury requiring dialysis when compared to NHW patients (OR: 2.53, 95% CI: 1.11-5.77, p = 0.027). There was no significant difference in terms of in-hospital mortality between NHB and Hispanic patients when compared to NHW patients. Notably, Hispanic populations experienced a higher mortality rate during the COVID-19 period.
Conclusion: Our study suggested significant differences in the outcomes of TTS across different racial groups. Hispanic populations experienced a higher mortality rate with TTS during the COVID-19 era. Further research should emphasize discovering the factors contributing to the observed disparities.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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