Blue Dye-Assisted Intraoperative Optical Coherence Tomography for Macular Surgery.

Autor: Pellegrini M; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Sant'Anna University Hospital, Ferrara, Italy.; Ospedali Privati Forlì 'Villa Igea', Department of Ophthalmology, Forlì, Italy., Adamo G; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Sant'Anna University Hospital, Ferrara, Italy., Sarti L; Sant'Anna University Hospital, Ferrara, Italy., Talli PM; Sant'Anna University Hospital, Ferrara, Italy., Nasini F; Sant'Anna University Hospital, Ferrara, Italy., Mura M; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Sant'Anna University Hospital, Ferrara, Italy.; King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde [Ophthalmologica] 2024 Aug 27, pp. 1-4. Date of Electronic Publication: 2024 Aug 27.
DOI: 10.1159/000541056
Abstrakt: Introduction: The purpose of this study was to evaluate whether vital blue dyes could enhance the contrast of intraoperative optical coherence tomography (OCT) during macular surgery.
Methods: Consecutive patients undergoing elective pars plana vitrectomy for vitreomacular interface disorders were enrolled. Intraoperative OCT was performed with the Artevo 800 microscope (Carl Zeiss Meditec AG, Jena, Germany) before and after injection of 0.2 mL of Trypan Blue and Brilliant Blue G Ophthalmic Solution. The OCT contrast ratio was measured with ImageJ, while the overall scan quality was subjectively classified using a 4-point scale.
Results: Ten eyes of 10 patients were enrolled in the study. The OCT contrast ratio was 9.39 ± 5.35 without blue dye and significantly improved to 14.31 ± 10.50 after blue dye injection (p = 0.027). The percentage of patients with a grade 4 scan quality also significantly improved (from 40% without blue dye to 90% with blue dye injection; p = 0.012).
Conclusion: The use of blue dyes during intraoperative OCT is an effective strategy for improving contrast and scan quality without affecting the surgical time and workflow.
(© 2024 S. Karger AG, Basel.)
Databáze: MEDLINE
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