Fetal epicardial fat thickness and modified myocardial performance index in late-onset fetal growth restriction.

Autor: Dal Y; Division of Perinatology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey., Akkuş F; Division of Perinatology, Department of Obstetrics and Gynecology, Necmettin Erbakan University Faculty of Medicine, Konya, Turkey., Karagün Ş; Division of Perinatology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey., Nessar AZ; Division of Perinatology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey., Karaca SG; Division of Perinatology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey., Kıllı MÇ; Division of Gynecological Oncology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey., Coşkun A; Division of Perinatology, Department of Obstetrics and Gynecology, Mersin University Faculty of Medicine, Mersin, Turkey.
Jazyk: angličtina
Zdroj: Journal of clinical ultrasound : JCU [J Clin Ultrasound] 2024 Nov-Dec; Vol. 52 (9), pp. 1321-1328. Date of Electronic Publication: 2024 Aug 27.
DOI: 10.1002/jcu.23804
Abstrakt: Aim: In our study, we aimed to investigate the value of fetal epicardial fat thickness (EFT) and modified myocardial performance index (mod-MPI) in fetal growth restriction (FGR) that develops after the 32nd week of gestation.
Materials and Methods: Fifty-six pregnant women who met the inclusion and exclusion criteria were included in the study and were divided into two groups: pregnancies diagnosed with FGR after the 32nd week of gestation (FGR group) and those without (control group). Demographic and obstetric histories, ultrasonographic and clinical characteristics, fetal EFT and mod-MPI values, and neonatal outcomes of the groups were recorded, and comparisons were made between the groups. Additionally, the diagnostic performance of fetal EFT value in late FGR was investigated.
Results: The FGR group had fetal EFT that was statistically significantly lower (1.11 ± 0.21 vs. 1.34 ± 0.23, p = 0.001). The FGR group had a significantly lower isovolumetric contraction time (ICT) (31.04 ± 6.88 vs. 35.14 ± 7.58, p = 0.048). The two groups' isovolumetric relaxation time (IRT), ejection time (ET), and mod-MPI values (p values 0.871, 0.55, and 0.750, respectively) were comparable. Receiver operating characteristic (ROC) analysis at a cutoff of 1.2 revealed 76.1% sensitivity and 74.2% specificity, respectively, for the diagnostic performance of the fetal EFT value in late-onset FGR. There was a positive predictive value (PPV) and negative predictive value (NPV) of 64.0% and 83.8%, respectively.
Conclusion: We found that fetal EFT was significantly lower in FGR and may be useful in diagnosing FGR. However, we observed that mode-MPI did not change in FGR.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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