Patterns of protein synthesis in the budding yeast cell cycle: variable or constant?
| Autor: | No EG; Department of Biochemistry and Biophysics, Texas A&M University TX, 77843 U.S.A., Blank HM; Department of Biochemistry and Biophysics, Texas A&M University TX, 77843 U.S.A., Polymenis M; Department of Biochemistry and Biophysics, Texas A&M University TX, 77843 U.S.A. |
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| Jazyk: | angličtina |
| Zdroj: | Microbial cell (Graz, Austria) [Microb Cell] 2024 Aug 20; Vol. 11, pp. 321-327. Date of Electronic Publication: 2024 Aug 20 (Print Publication: 2024). |
| DOI: | 10.15698/mic2024.08.835 |
| Abstrakt: | Proteins are the principal macromolecular constituent of proliferating cells, and protein synthesis is viewed as a primary metric of cell growth. While there are celebrated examples of proteins whose levels are periodic in the cell cycle (e.g., cyclins), the concentration of most proteins was not thought to change in the cell cycle, but some recent results challenge this notion. The 'bulk' protein is the focus of this article, specifically the rate of its synthesis, in the budding yeast Saccharomyces cerevisiae . Competing Interests: The authors have no conflicts to declare. |
| Databáze: | MEDLINE |
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