A Paradox Unveiled: A Case Report of Cerebral Infarctions in a Patient With Severe Thrombocytopenia.

Autor: Chapiolkina V; Internal Medicine, St. Barnabas Hospital Health System, New York, USA., Mekonen YF; Internal Medicine, St. Barnabas Hospital Health System, New York, USA., Guevara N; Medicine, St. Barnabas Hospital Health System, New York, USA., Perez E; Internal Medicine, St. Barnabas Hospital Health System, New York, USA., Sanchez J; Internal Medicine, St. Barnabas Hospital Health System, New York, USA., Tole MC; Internal Medicine, St. Barnabas Hospital Health System, New York, USA., Vigoda I; Oncology, St. Barnabas Hospital Health System, New York, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jul 24; Vol. 16 (7), pp. e65283. Date of Electronic Publication: 2024 Jul 24 (Print Publication: 2024).
DOI: 10.7759/cureus.65283
Abstrakt: Thrombocytopenia is a condition in which the platelet count is less than 150,000/μL, which can be congenital or acquired. The condition can be further sub-classified. Nevertheless, the causes include infection, medication-mediated, liver diseases, or heart diseases. Moreover, diagnosis is straightforward only on a few occasions. Here, we are presenting a patient with a conundrum of immune thrombocytopenia (ITP) and a stroke. A 75-year-old female patient with a past medical history of hypertension was brought to the emergency department (ED) for altered mental status (AMS). Initial blood workup showed a platelet count of 27,000/μL and hemoglobin level of 6.2 g/dl, and brain magnetic resonance imaging (MRI) revealed ischemic stroke. Rarely, ITP patients can paradoxically develop arterial and venous thrombosis. Hence, physicians must remain vigilant in promptly and accurately diagnosing thrombotic events in ITP to ensure appropriate treatment, including antiplatelet and anticoagulant therapy, alongside ITP-specific interventions to improve outcomes.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Chapiolkina et al.)
Databáze: MEDLINE