Management of Myocardial Infarction: Emerging Paradigms for the Future.

Autor:	Upadhyaya VD; Hackensack Meridian Health -Jersey Shore University Medical Center, Neptune City, New Jersey, US., Wong C; Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, US., Zakir RM; Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, US., Aghili N; Colorado Heart and Vascular, St. Anthony Hospital, Lakewood, Colorado, US., Faraz H; Hackensack University Medical Center, Hackensack, New Jersey, US., Kapur NK; Cardiovascular Center, Tufts Medical Center, Boston, Massachusetts, US.
Jazyk:	angličtina
Zdroj:	Methodist DeBakey cardiovascular journal [Methodist Debakey Cardiovasc J] 2024 Aug 20; Vol. 20 (4), pp. 54-63. Date of Electronic Publication: 2024 Aug 20 (Print Publication: 2024).
DOI:	10.14797/mdcvj.1393
Abstrakt:	Despite significant advancements in managing acute ST-segment elevation myocardial infarctions, the prevalence of heart failure has not decreased. Emerging paradigms with a focus on reducing infarct size show promising evidence in the improvement of the incidence of heart failure after experiencing acute coronary syndromes. Limiting infarct size has been the focus of multiple clinical trials over the past decades and has led to left ventricular (LV) unloading as a potential mechanism. Contemporary use of microaxial flow devices for LV unloading has suggested improvement in mortality in acute myocardial infarction complicated by cardiogenic shock. This review focuses on clinical data demonstrating evidence of infarct size reduction and highlights ongoing clinical trials that provide a new therapeutic approach to the management of acute myocardial infarction. Competing Interests: The other authors have no competing interests to declare. (Copyright: © 2024 The Author(s).)
Databáze:	MEDLINE
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