Complication, vertical bone gain, volumetric changes after vertical ridge augmentation using customized reinforced PTFE mesh or Ti-mesh. A non-inferiority randomized clinical trial.

Autor: Cucchi A; Private Practice, Bologna, Italy., Bettini S; Implant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy., Tedeschi L; Private Practice, Bologna, Italy., Urban I; Department of Periodontology and Oral Medicine, University of Michigan, Ann Arbor, Michigan, USA., Franceschi D; Department of Experimental and Clinic Medicine, University of Florence, Florence, Italy., Fiorino A; Department of Neuroscience and Reproductive and Odontostomatological Sciences, 'Federico II' University of Naples, Naples, Italy., Corinaldesi G; Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
Jazyk: angličtina
Zdroj: Clinical oral implants research [Clin Oral Implants Res] 2024 Dec; Vol. 35 (12), pp. 1616-1639. Date of Electronic Publication: 2024 Aug 23.
DOI: 10.1111/clr.14350
Abstrakt: Objective: The aim of this non-inferiority randomized clinical trial was to compare the surgical and healing complications, vertical bone gain, and volumetric bone changes after vertical ridge augmentation using two different approaches: customized Ti-reinforced d-PTFE mesh versus customized CAD/CAM Ti-mesh.
Materials and Methods: Fifty patients with vertical bone defects were randomly treated with Ti-reinforced d-PTFE mesh (control group) or CAD/CAM Ti-mesh (test group) and a mix of autogenous bone and deproteinized bovine bone matrix. Surgical and healing complication rates (SCR-HCR), vertical bone gain (VBG), regenerated bone volume (RBV), and regeneration rates (RR and ERR) were recorded and analysed [significance level (α) of 0.05].
Results: Of the 50 patients, 48 underwent bone augmentation surgery. SCR were 4% and 12% in PTFE and Ti-mesh, whereas HCR were 12.5% and 8.3%. VBG were 5.79 ± 1.71 mm (range: 3.2-8.8 mm) in the PTFE group and 5.18 ± 1.61 mm (range: 3.1-8.0 mm) in the Ti-mesh group (p = .233), whereas RBV were 1.46 ± 0.48 cc and 1.26 ± 0.55. RR was 99.5% and 87.0%, demonstrating a statistically significant difference (p = .013). Finally, the values related to pseudo-periosteum, bone density, and implant stability were similar in the two study groups. Osseointegration rates were 98.2% and 98.3%.
Conclusions: This study confirmed the non-inferiority of customized CAD/CAM titanium meshes with respect to reinforced PTFE meshes in terms of surgical and healing complications. Although PTFE meshes showed higher vertical bone gain and regeneration rates than Ti-meshes, no significant differences were found.
(© 2024 The Author(s). Clinical Oral Implants Research published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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