A nomogram prediction model for postoperative seroma/hematoma in elderly subjects after TAPP.

Autor: Ge Y; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China., Zhou Y; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China., Liu J; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China., Shen W; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China., Gu H; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China., Cheng G; Department of Hernia and Pediatric Surgery, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou Clinical Medical School of Nanjing Medical University, No. 366 Taihu Road, Taizhou City, 225300, Jiangsu Province, China. chengguochang@hotmail.com.
Jazyk: angličtina
Zdroj: Hernia : the journal of hernias and abdominal wall surgery [Hernia] 2024 Oct; Vol. 28 (5), pp. 1961-1967. Date of Electronic Publication: 2024 Aug 23.
DOI: 10.1007/s10029-024-03134-5
Abstrakt: Background: Formation of seroma/hematoma is one of the most common postoperative complications following laparoscopic inguinal hernia repair. This study aimed to identify risk factors associated with seroma/hematoma and construct a prediction model.
Methods: Elderly subjects undergoing laparoscopic Transabdominal preperitoneal Patch Plasty (TAPP) were included in this study. The observation endpoint was set as the occurrence of seroma/hematoma within 3 months after TAPP surgery. Independent risk factors were identified through preliminary univariate screening and binary logistic regression analysis. These risk factors were then used to construct a nomogram predictive model using R software.
Results: A total of 330 patients were included in the analysis, of which 51 developed seroma/hematoma, resulting in an incidence rate of 15.5%. Obesity (OR: 3.54, 95%CI: 1.45-8.66, P = 0.006), antithrombotic drug use (OR: 2.73, 95%CI: 1.06-7.03, P = 0.037), C-reactive protein (CRP) ≥ 8 (OR: 2.72, 95%CI: 1.04-7.10, P = 0.041, albumin/fibrinogen ratio (AFR) < 7.85 (OR: 2.99, 95%CI: 1.28-7.00, P = 0.012), and lymphocyte/monocyte ratio (LMR) < 4.05 (OR: 12.62, 95%CI: 5.69-28.01, P < 0.001) were five independent risk factors for seroma/hematoma. The nomogram model has well predictive value for seroma/hematoma, with an AUC of 0.879.
Conclusions: The nomogram model based on obesity, antithrombotic drug, CRP, AFR, and LMR has a proved good predictive value and it has potential in clinical practice.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.)
Databáze: MEDLINE
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