Wideband radiofrequency pulse sequence for evaluation of myocardial scar in patients with cardiac implantable devices.

Autor: Shah ND; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, United States., Krishnam M; Department of Radiology, Stanford University, Stanford, CA, United States., Ambale Venkatesh B; Department of Medicine, Division of Cardiovascular Medicine, Johns Hopkins University, Baltimore, MD, United States., Khan F; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, United States., Smith M; Department of Radiology, Stanford University, Stanford, CA, United States., Jones DR; Department of Radiology, Stanford University, Stanford, CA, United States., Koon P; GE Healthcare, Menlo Park, CA, United States., Mao X; GE Healthcare, Menlo Park, CA, United States., Janich MA; GE Healthcare, Munich, Germany., Brau ACS; GE Healthcare, Menlo Park, CA, United States., Salerno M; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, United States., Dash R; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, United States., Chan F; Department of Radiology, Stanford University, Stanford, CA, United States., Yang PC; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, United States.
Jazyk: angličtina
Zdroj: Frontiers in radiology [Front Radiol] 2024 Aug 07; Vol. 4, pp. 1327406. Date of Electronic Publication: 2024 Aug 07 (Print Publication: 2024).
DOI: 10.3389/fradi.2024.1327406
Abstrakt: Background: Cardiac magnetic resonance is a useful clinical tool to identify late gadolinium enhancement in heart failure patients with implantable electronic devices. Identification of LGE in patients with CIED is limited by artifact, which can be improved with a wide band radiofrequency pulse sequence.
Objective: The authors hypothesize that image quality of LGE images produced using wide-band pulse sequence in patients with devices is comparable to image quality produced using standard LGE sequences in patients without devices.
Methods: Two independent readers reviewed LGE images of 16 patients with CIED and 7 patients without intracardiac devices to assess for image quality, device-related artifact, and presence of LGE using the American Society of Echocardiography/American Heart Association 17 segment model of the heart on a 4-point Likert scale. The mean and standard deviation for image quality and artifact rating were determined. Inter-observer reliability was determined by calculating Cohen's kappa coefficient. Statistical significance was determined by T -test as a p {less than or equal to} 0.05 with a 95% confidence interval.
Results: All patients underwent CMR without any adverse events. Overall IQ of WB LGE images was significantly better in patients with devices compared to standard LGE in patients without devices ( p  = 0.001) with reduction in overall artifact rating ( p  = 0.05).
Conclusion: Our study suggests wide-band pulse sequence for LGE can be applied safely to heart failure patients with devices in detection of LV myocardial scar while maintaining image quality, reducing artifact, and following routine imaging protocol after intravenous gadolinium contrast administration.
Competing Interests: Authors XM, MJ and AB were employed by company GE Healthcare. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
(© 2024 Shah, Krishnam, Ambale Venkatesh, Khan, Smith, Jones, Koon, Mao, Janich, Brau, Salerno, Dash, Chan and Yang.)
Databáze: MEDLINE