[Biobanking in clinical trials involving multiple sclerosis patients].

Autor: Kamenskikh EM; Siberian State Medical University, Tomsk, Russia., Krygina AY; Siberian State Medical University, Tomsk, Russia., Gomboeva SC; Siberian State Medical University, Tomsk, Russia., Zhailebaeva D; Siberian State Medical University, Tomsk, Russia., Koval DP; Siberian State Medical University, Tomsk, Russia., Kicherov NA; Siberian State Medical University, Tomsk, Russia., Otchurzhap CN; Siberian State Medical University, Tomsk, Russia., Birulina YG; Siberian State Medical University, Tomsk, Russia., Alifirova VM; Siberian State Medical University, Tomsk, Russia.
Jazyk: ruština
Zdroj: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2024; Vol. 124 (7. Vyp. 2), pp. 7-15.
DOI: 10.17116/jnevro20241240727
Abstrakt: Investigation of multiple sclerosis (MS) pathogenesis requires sophisticated analytical tools of precision medicine, such as omics research, which include genomics, microbiomics and metabolomics (proteomics, lipidomics and glycomics). Such sensitive methods are based on careful preanalytical work with biomaterials to maintain quality and obtain objective results. Implementation of biobanking as a universal method for working with biomaterials will help to standardize the stages of research, compare different scientific team's results. Collaboration of MS researchers with large biobanks can also help to conduct multicenter and long-term prospective studies, to include a wide number of patients. In this article, we analyze the experience of biobanking practice technologies in studies of MS patients and share the experience of partnership between the Center for MS of the Tomsk Region and the Bank of Biological Material of the Siberian State Medical University.
Databáze: MEDLINE