Observational study of intracranial compliance analysis in neurologically healthy pediatric patients using a non-invasive device.

Autor: Karuta SCV; Department of Medicine Course, Pequeno Príncipe Faculdades, Curitiba, Paraná, Brazil. sizetecv@yahoo.com.br.; Department of Neurology, Hospital Pequeno Príncipe, Curitiba, PR, Brazil. sizetecv@yahoo.com.br.; Department of Clinical Research, Hospital Pequeno Príncipe, Rua Desembargador Motta, 1070 - Água Verde, 6° Andar, Curitiba, PR, 80250-060, Brazil. sizetecv@yahoo.com.br., Folchini CM; Department of Clinical Research, Hospital Pequeno Príncipe, Rua Desembargador Motta, 1070 - Água Verde, 6° Andar, Curitiba, PR, 80250-060, Brazil., Fachi MM; Value Management Office, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Okumura LM; Value Management Office, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Manços GR; Innovation Office, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Ricieri MC; Department of Clinical Research, Hospital Pequeno Príncipe, Rua Desembargador Motta, 1070 - Água Verde, 6° Andar, Curitiba, PR, 80250-060, Brazil.; Value Management Office, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Motta FA; Department of Clinical Research, Hospital Pequeno Príncipe, Rua Desembargador Motta, 1070 - Água Verde, 6° Andar, Curitiba, PR, 80250-060, Brazil.; Value Management Office, Hospital Pequeno Príncipe, Curitiba, PR, Brazil., Maeda AK; Department of Neurology, Hospital Pequeno Príncipe, Curitiba, PR, Brazil.; Department of Neurosurgery, Hospital Pequeno Príncipe, Curitiba, PR, Brazil.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Aug 22; Vol. 14 (1), pp. 19482. Date of Electronic Publication: 2024 Aug 22.
DOI: 10.1038/s41598-024-69938-8
Abstrakt: Information about the morphology of the intracranial pressure waveform, as well as the variations in intracranial pressure (ICP) and compliance in pediatric patients are essential to diagnose and predict the progression of various neurological conditions. However, there is no information on the morphology of the IP waveform in neurologically healthy pediatric patients. In the present study, intracranial compliance was therefore analyzed in neurologically healthy patients with the aid of a noninvasive device. The study was an observational, cross-sectional study. Fifty-five neurologically healthy participants were included. Data on intracranial compliance with the patient in two positions, lying down (0°) and seated (45°), were collected with a noninvasive extracranial sensor, which allowed the intracranial pressure waveforms to be recorded. The values of the ratio P2/P1 were then analyzed. A questionnaire (with a scale from zero to ten, where ten corresponds to the highest level of satisfaction) was applied for patients to evaluate their satisfaction with the sensor. Patients were 10 years old (average), and most of them were (58%). Mean P2/P1 ratio was 0.94 (sd = 0.14) in the supine position and 0.91 (sd = 0.15) in the seated position. Participants were satisfied with the length of time for which the equipment was used (9.8, sd = 0.71). The device did not cause any discomfort. The noninvasive method used was well accepted by the patients. Intracranial compliance values were determined by analysis of the P2/P1 ratio in neurologically healthy pediatric population.Trial registration: Brazilian Registry of Clinical Trials Identifier: RBR-5j74ddg.
(© 2024. The Author(s).)
Databáze: MEDLINE
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