Adsorption mechanism of cefradine on three microplastics: A combined molecular dynamics simulation and density functional theory calculation study.

Autor: Zhao G; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China., Li W; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China., Xu C; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China., Qin Q; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China., Fan W; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China., Li X; Key Laboratory of Industrial Ecology and Environmental Engineering, Ministry of Education, College of environmental science and engineering, Dalian University of Technology, Dalian 116023, China., Zhao D; College of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China. Electronic address: zhaodan@dlou.edu.cn.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Nov 15; Vol. 951, pp. 175690. Date of Electronic Publication: 2024 Aug 22.
DOI: 10.1016/j.scitotenv.2024.175690
Abstrakt: Microplastics and antibiotics are receiving increasing attention as two emerging pollutants in the aquatic ecosystem. The absorption of antibiotics by microplastics can potentially intensify their impact on marine organisms and human health. However, the detailed mechanisms underlying this interaction remain to be elucidated. Through molecular dynamics (MD) simulations and density functional theory (DFT) calculations, this study investigated the adsorption of cefradine (CED) onto three typical microplastics (MPs)-polyethylene (PE), polypropylene (PP), and polyamide (PA). The results of the molecular dynamics simulations showed that the interaction energy between CED and microplastics followed the order of PA-CED > PP-CED > PE-CED, indicating that PA microplastics had the highest adsorption capacity for CED antibiotics. The total energy contribution of the microplastics-cefradine (MPs-CED) systems suggested that the van der Waals and electrostatic interactions were the two primary mechanisms for the adsorption of CED by these three microplastics. In DFT calculations, the adsorption of CED on PA was found to be significantly influenced by both electrostatic and van der Waals effects, while the main driving force in the adsorption of PE and PP is van der Waals effect. In addition, IGMH analysis and AIM topological analysis confirmed that the adsorption of CED on PA relied heavily on the synergistic effect of hydrogen bonding and the van der Waals effect. The findings of this study validate the results obtained from molecular dynamics simulations, laying a foundation for a comprehensive exploration of the interaction mechanisms between microplastics and organic pollutants by integrating MD simulations and DFT calculations.
Competing Interests: Declaration of competing interest All authors disclosed no relevant relationships.
(Copyright © 2024. Published by Elsevier B.V.)
Databáze: MEDLINE
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