Prevalence of Musculoskeletal Symptoms in Patients With Hidradenitis Suppurativa and Associated Factors: Cross-Sectional Study.

Autor:	McKee H; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Eder L; Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Women's College Research Institute, Toronto, ON, Canada., Jerome D; Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Women's College Research Institute, Toronto, ON, Canada., Mirza RD; Division of Rheumatology, Sunnybrook Hospital, Toronto, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada., Obetta C; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Pek E; Division of Rheumatology, Sunnybrook Hospital, Toronto, ON, Canada., Piguet V; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Division of Dermatology, Department of Medicine, Women's College Hospital, Toronto, ON, Canada., Alhusayen R; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.; Sunnybrook Research Institute, Toronto, ON, Canada.
Jazyk:	angličtina
Zdroj:	JMIR dermatology [JMIR Dermatol] 2024 Aug 22; Vol. 7, pp. e58989. Date of Electronic Publication: 2024 Aug 22.
DOI:	10.2196/58989
Abstrakt:	The prevalence of and factors associated with musculoskeletal (MSK) symptoms in patients with hidradenitis suppurativa (HS) have yet to be elucidated. Given the association between HS and inflammatory comorbidities, understanding the burden of MSK symptoms in patients with HS is crucial for patient-centered care. Our objective was to describe the prevalence of and factors associated with MSK symptoms in patients with HS. A cross-sectional study of 78 consecutive patients recruited between November 2021 and February 2023 with a dermatology-confirmed diagnosis of HS, irrespective of MSK symptoms, was performed. The average age of participants (n=78) was 37 (SD 12.2) years, and the average age at symptom onset was 23 (SD 12.1) years; 54% (n=42) of participants identified as women, and 46% (n=36) as men. The most common comorbidities included depression (n=17, 22%) and preexisting arthritis (n=12, 16%). Approximately 24% (n=18) of participants reported prolonged morning stiffness. In a multivariate regression, depression was significantly associated with morning stiffness (odds ratio [OR] 6.1, 95% CI 1.4-26.1; P=.02), while female sex was significantly associated with arthralgia (OR 19.1, 95% CI 1.6-235.2; P=.02). Every patient with depression reported arthralgia. We highlight the high prevalence of MSK symptoms among patients with HS and note the interplay between depression and MSK symptoms, with each one potentially contributing to the other. (©Hayley McKee, Lihi Eder, Dana Jerome, Reza D Mirza, Chikaodili Obetta, Elisabeth Pek, Vincent Piguet, Raed Alhusayen. Originally published in JMIR Dermatology (http://derma.jmir.org), 22.08.2024.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu