If patients had a choice - Treatment satisfaction and patients' preference in therapy of actinic keratoses.

Autor: Lang BM; Department of Dermatology, University Medical Center Mainz, Mainz, Germany., Zielbauer S; Department of Dermatology, University Medical Center Mainz, Mainz, Germany., Stege H; Department of Dermatology, University Medical Center Mainz, Mainz, Germany., Grabbe S; Department of Dermatology, University Medical Center Mainz, Mainz, Germany., Staubach P; Department of Dermatology, University Medical Center Mainz, Mainz, Germany.
Jazyk: angličtina
Zdroj: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG [J Dtsch Dermatol Ges] 2024 Oct; Vol. 22 (10), pp. 1362-1368. Date of Electronic Publication: 2024 Aug 22.
DOI: 10.1111/ddg.15457
Abstrakt: Background: Actinic keratoses (AK) are increasing in incidence and represent the most common (pre-)cancerous lesion in the fair-skinned population, with a high unmet medical need. In order to increase treatment adherence, it is very important to assess patients' therapy-related evaluations of different treatment options.
Patients and Methods: 100 patients with AK who were treated with at least two different treatment options were included. They rated their therapies using the Treatment Satisfaction Questionnaire for Medication (TSQM, maximum 100 points per category) and a Likert scale (LS, 1  =  very satisfied; 6  =  not satisfied). Patients were also asked about their needs in terms of treatment goal, cost, type, duration, and location of treatment.
Results: 81% of the study participants were male and on average 74 years old. 95% had field cancerization. Eight frequently used therapy procedures were evaluated by the patients (surgery, cryotherapy, various topical agents, photodynamic therapy). The TSQM satisfaction scores ranged from 78.47 ± 16.07 (surgical procedures) to 53.03 ± 22.13 (diclofenac-HA). Statistically significant differences between the procedures were only found in the area of efficacy. Side effects were classified as low. Low recurrence rate and safe removal were the most important treatment goals (LS: 1.18 ± 0.44 and 1.27 ± 0.53, respectively).
Conclusions: Understanding patient preferences is essential for adherence and is therefore of great importance for the success of AK therapy. Personalized approaches should be considered in the choice of therapy.
(© 2024 The Authors. Journal der Deutschen Dermatologischen Gesellschaft published by Wiley‐VCH GmbH on behalf of Deutsche Dermatologische Gesellschaft.)
Databáze: MEDLINE
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