EN FACE OPTICAL COHERENCE TOMOGRAPHY MORPHOLOGY OF MACULAR PUCKER CORRELATES WITH METAMORPHOPSIA: Possible Role of the Henle Fiber Layer.

Autor:	Govetto A; Doheny Eye Institute, University of California Los Angeles, Pasadena, California., Lucchini S; Doheny Eye Institute, University of California Los Angeles, Pasadena, California., Sebag J; Department of Ophthalmology, Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.; VMR Institute for Vitreous Macula Retina, Huntington Beach, California.; Ophthalmology Department, Careggi University Hospital, University of Florence, Florence, Italy., Gianfrate F; Doheny Eye Institute, University of California Los Angeles, Pasadena, California., Ranno S; Doheny Eye Institute, University of California Los Angeles, Pasadena, California., Carini E; Doheny Eye Institute, University of California Los Angeles, Pasadena, California., Virgili G; Department of Ophthalmology, Humanitas Gavazzeni, Humanitas University, Bergamo, Italy., Romano MR; Department of Ophthalmology, Vitreoretinal Division, Circolo and Macchi Foundation Hospital., Sarraf D; Retinal Disorders and Ophthalmic Genetics Division, Stein Eye Institute, University of California Los Angeles, Los Angeles, California; and.; Greater Los Angeles VA Healthcare Center (D.S.), Los Angeles, California., Radice P; Doheny Eye Institute, University of California Los Angeles, Pasadena, California.
Jazyk:	angličtina
Zdroj:	Retina (Philadelphia, Pa.) [Retina] 2024 Sep 01; Vol. 44 (9), pp. 1513-1520.
DOI:	10.1097/IAE.0000000000004160
Abstrakt:	Purpose: To describe macular pucker contraction patterns with en face optical coherence tomography (OCT), to provide a correlation with metamorphopsia scores, and to discuss the protective role of the Henle fiber layer (HFL) against tangential traction. Methods: Retrospective, institutional, observational, and consecutive case series. Clinical charts, M-charts scores, and structural and en face OCT imaging of patients diagnosed with macular pucker were reviewed. Results: A 120 eyes of 114 consecutive patients diagnosed with macular pucker were included. En face OCT patterns of macular pucker contraction were foveal in 51 of 120 eyes (42.5%) and extrafoveal in 69 of 120 eyes (57.5%). Foveal macular puckers had regular, a concentric, circle morphology in the HFL (46/51 eyes, 90.2%), whereas extrafoveal membranes had irregular, distorted, circular HFL morphology (62/69 eyes, 89.8%; P < 0.001). Foveal contraction morphology and regular HFL pattern, as well as extrafoveal contraction morphology and an irregular HFL pattern, highly correlated one with another (P < 0.001 in both cases). Foveal macular puckers with regular HFL patterns had significantly less vertical and horizontal M-charts scores as compared with extrafoveal membranes with irregular HFL (P < 0.001 in both cases). Ellipsoid zone and external limiting membrane defects were rare in the parafoveal region (5/120 eyes, 4.2%). Visual acuity did not correlate with metamorphopsia scores (P = 0.903). Conclusion: En face OCT imaging identifies macular pucker contraction patterns that correlate with metamorphopsia scores and that can be used alongside the current structural OCT staging system to guide clinicians in the surgical decision-making process.
Databáze:	MEDLINE
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