Platelet-rich Plasma as a Treatment Modality for Wound Healing: An Open Randomized Controlled Trial.
| Autor: | Jose AM; Medical Graduate, Jawaharlal Nehru Medical College (DMIHER), Sawangi (Meghe), Maharashtra, India, Corresponding Author., Mahakalkar CC; Professor, Department of Surgery, Jawaharlal Nehru Medical College (DMIHER), Sawangi (Meghe), Maharashtra, India. |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of the Association of Physicians of India [J Assoc Physicians India] 2024 Aug; Vol. 72 (8), pp. e26-e30. |
| DOI: | 10.59556/japi.72.0428 |
| Abstrakt: | Introduction: Unlike conventional management protocols, like dressings, wound debridement, and skin grafting that do not facilitate healing, platelet-rich plasma (PRP) directly feeds growth factors to enhance wound healing. Materials and Methods: An open randomized controlled trial with a sample size of 60 was carried out on patients with a wound surface area ≤10 × 10 cm 2 with 30 participants in each. The PRP group (PRPG) was given autologous PRP using the infiltration technique, and the control group (CG) was treated using conventional dressings. Results: The PRPG showed a reduction from 1421 to 661 mm 2 , whereas the CG showed a decrease from 1710 to 1478 mm 2 on day 30. The PRP group had a decreased hospital stay ( n = 14) in comparison to the CG ( n = 17.5 days). The rate of epithelization (mean) is 11.12 mm 2 /day in the CG and 34.026 mm 2 /day in the PRPG. Conclusion: Platelet-rich plasma (PRP) can be considered a primary modality for wound management because of decreased length of hospital stay, analgesic effects, fastened rate of healing, and absence of adverse reactions. (© Journal of the Association of Physicians of India 2024.) |
| Databáze: | MEDLINE |
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