The potential longevity-promoting hypoxic-hypercapnic environment as a measure for radioprotection.

Autor: David E; Nuclear Research Center Negev (NRCN), P.O. Box 9001, 8419001, Beer-Sheva, Israel. elroeid@gmail.com., Wolfson M; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, 8410501, Beer Sheva, Israel., Muradian KK; Department of Aging Biology and Experimental Life Extension, Institute of Gerontology, NAMS of Ukraine, Kiev, 04114, Ukraine., Fraifeld VE; The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, 8410501, Beer Sheva, Israel.
Jazyk: angličtina
Zdroj: Biogerontology [Biogerontology] 2024 Oct; Vol. 25 (5), pp. 891-898. Date of Electronic Publication: 2024 Aug 20.
DOI: 10.1007/s10522-024-10129-3
Abstrakt: Many biological mechanisms of aging well converge with radiation's biological effects. We used scientific insights from the field of aging to establish a novel hypoxic-hypercapnic environment (HHE) concept for radioprotection. According to this concept, HHE which possesses an anti-aging and longevity-promoting potential, should also act as a radiomitigator and radioprotector. As such, it might contribute greatly to the safety and wellbeing of individuals exposed to high levels of radiation, whether in planned events (e.g. astronauts) or in unplanned events (e.g. first responders in nuclear accidents).
(© 2024. The Author(s).)
Databáze: MEDLINE
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