Exploring Analgesic Use Patterns Among Cancer Survivors With Chronic Chemotherapy-Induced Peripheral Neuropathy.

Autor: Knoerl R; University of Michigan in Ann Arbor., Sohn MB; University of Rochester Medical Center., Foust M; Upstate Carolina Consortium National Cancer Institute Community Oncology Research Program., Francar L; Hospital Sisters Health System St. Vincent Hospital., O'Rourke MA; University of South Carolina., Morrow GM; University of Rochester Medical Center., Mustian KM; University of Rochester Medical Center., Gauthier L; Université Laval., Gewandter JS; University of Rochester Medical Center.
Jazyk: angličtina
Zdroj: Oncology nursing forum [Oncol Nurs Forum] 2024 Aug 15; Vol. 51 (5), pp. 445-450.
DOI: 10.1188/24.ONF.445-450
Abstrakt: Objectives: To explore cancer survivors' historical and current use of analgesics for chronic chemotherapy-induced peripheral neuropathy (CIPN).
Sample & Setting: 142 post-treatment cancer survivors who received neurotoxic chemotherapy and were experiencing moderate to severe CIPN.
Methods & Variables: Participants completed the Treatment-Induced Neuropathy Assessment Scale at baseline and reported all analgesics used to manage CIPN. Frequency of historical or current prescription analgesic use for chronic CIPN was described and stratified by CIPN pain severity.
Results: At baseline, 31% of participants reported historical use of analgesics for CIPN and 46% of participants were currently using analgesics for CIPN. Gabapentin was the most frequently used analgesic, historically (20%) and currently (34%), and duloxetine was used less frequently (6% historical use, 10% current use). Many participants with severe pain (59%) reported using analgesics for CIPN.
Implications for Nursing: Duloxetine, the first-line treatment for chronic CIPN pain, was used less frequently than gabapentin, a common prescription analgesic for neuropathic pain. Further research is needed to determine strategies to promote the implementation of evidence-based CIPN treatments in clinical practice.
Databáze: MEDLINE