Metastatic Adenocarcinoma of the Prostate Masquerading as a Splenic Flexure Colonic Polyp: A Diagnostic Conundrum.
| Autor: | Shkoukani ZW; Department of Urology, St Helens and Knowsley Teaching Hospitals NHS Trust, Liverpool, GBR., Chamsin A; Department of Urology, St Helens and Knowsley Teaching Hospitals NHS Trust, Liverpool, GBR., Abdulmajed MI; Department of Urology, St Helens and Knowsley Teaching Hospitals NHS Trust, Liverpool, GBR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Jul 19; Vol. 16 (7), pp. e64959. Date of Electronic Publication: 2024 Jul 19 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.64959 |
| Abstrakt: | Metastasis of prostate cancer to the gastrointestinal tract is infrequently described in the literature, with only a limited number of cases reporting metastasis to the rectum. We present a rare case of a 74-year-old man initially presenting with symptomatic anemia and weight loss. A colonoscopy revealed a sessile polyp in the splenic flexure. Microscopic examination of the specimen showed micro-acinar structures, and immunohistochemical staining was positive for prostate-specific antigen (PSA) and NKX3.1. Subsequently, elevated serum PSA levels and staging computed tomography (CT) findings, in conjunction with histopathological analysis, confirmed a diagnosis of metastatic prostate adenocarcinoma. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Shkoukani et al.) |
| Databáze: | MEDLINE |
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