Association between E-Cigarette Smoking and Insulin Resistance Using the Triglyceride-Glucose Index in Korean Adults: Korea National Health and Nutrition Examination Survey.

Autor:	Lim D; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Choi JI; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Kwon RJ; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Lee SY; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea.; Department of Family Medicine, Pusan National University School of Medicine, Yangsan, Korea.; Department of Medical Education, Pusan National University School of Medicine, Yangsan, Korea., Cho YH; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea.; Department of Family Medicine, Pusan National University School of Medicine, Yangsan, Korea., Park EJ; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Lee Y; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Lee SR; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Son SM; Department of Family Medicine and Biomedical Research Institute, Pusan National University Yangsan Hospital, Yangsan, Korea., Kim YJ; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Lee JG; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Yi YH; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Tak YJ; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Lee SH; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Kim GL; Department of Family Medicine, Pusan National University Hospital, Busan, Korea., Ra YJ; Department of Family Medicine, Pusan National University Hospital, Busan, Korea.
Jazyk:	angličtina
Zdroj:	Korean journal of family medicine [Korean J Fam Med] 2024 Aug 20. Date of Electronic Publication: 2024 Aug 20.
DOI:	10.4082/kjfm.23.0141
Abstrakt:	Background: Insulin resistance contributes to the development of cardiovascular disease and type 2 diabetes mellitus. Smoking leads to an increase in triglyceride levels, which, in turn, increases insulin resistance. Although the number of e-cigarette users has increased in recent years, few studies have investigated the association between ecigarette use and insulin resistance. Therefore, this study aimed to determine the association between e-cigarette use and insulin resistance using the triglyceride-glucose (TyG) index in Korean adults. Methods: This study included 4,404 healthy adults aged ≥20 years who participated in the Korea National Health and Nutrition Examination Survey between 2019 and 2020. Participants were categorized as never-smokers or ecigarette users, and the TyG index was categorized into low- and high-TyG index groups according to the median value (9.22). A logistic regression analysis was performed to determine the association between e-cigarette smoking and insulin resistance. Results: E-cigarette users had a higher TyG index than never smokers (e-cigarette: mean=3.95; never: mean=9.18; P<0.001). The e-cigarette users had a higher risk of being in the high TyG index group than never-smokers (odds ratio [OR], 1.38; 95% confidence interval [CI], 1.03-1.84). In the subgroup analysis stratified by sex, age, and body mass index, a higher OR for a high TyG index was observed in men (OR, 1.46; 95% CI, 1.03-2.08) and individuals aged 60 years or older (OR, 3.74; 95% CI, 1.14-12.30). Conclusion: Our findings suggest that e-cigarette use is significantly associated with insulin resistance.
Databáze:	MEDLINE
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