Approach to pancytopenia: From blood tests to the bedside.

Autor: Chew S; Croydon Health Services NHS Trust, United Kingdom. Electronic address: shaun.chew@nhs.net., Kamangar M; Croydon Health Services NHS Trust, United Kingdom.
Jazyk: angličtina
Zdroj: Clinical medicine (London, England) [Clin Med (Lond)] 2024 Sep; Vol. 24 (5), pp. 100235. Date of Electronic Publication: 2024 Aug 17.
DOI: 10.1016/j.clinme.2024.100235
Abstrakt: Pancytopenia is an uncommon abnormality detected on a full blood count. Features of presentation tend to be non-specific, and are due to impaired functions of the cell lines involved. These can include fatigue, infection and bleeding. However, the aetiology of pancytopenia is extensive. This narrative review aims to provide a minimally invasive diagnostic algorithm for generalist clinicians to approach pancytopenia, including investigations into the underlying aetiology, and when a referral to the haematologist is warranted for further investigations such as bone marrow aspiration and trephine biopsy.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE