Reverse Correlation Characterizes More Complete Tinnitus Spectra in Patients.

Autor:	Barnett NV; Department of Biomedical Engineering (BME)Worcester Polytechnic Institute (WPI) Worcester MA 01609 USA., Hoyland A; Department of Biomedical Engineering (BME)Worcester Polytechnic Institute (WPI) Worcester MA 01609 USA.; Clarifai, Inc. Wilmington DE 19808 USA., Chari DA; University of Massachusetts Chan Medical School Worcester MA 01609 USA.; Massachusetts Eye and Ear Infirmary Boston MA 02114 USA., Parrell B; Department of Communication Sciences and Disorders and the Waisman CenterUniversity of Wisconsin Madison WI 53707 USA., Lammert AC; Department of Mathematics and Computer ScienceCollege of the Holy Cross Worcester MA 01610 USA.
Jazyk:	angličtina
Zdroj:	IEEE open journal of engineering in medicine and biology [IEEE Open J Eng Med Biol] 2024 Jul 18; Vol. 5, pp. 589-592. Date of Electronic Publication: 2024 Jul 18 (Print Publication: 2024).
DOI:	10.1109/OJEMB.2024.3427318
Abstrakt:	Goal: We validate a recent reverse correlation approach to tinnitus characterization by applying it to individuals with clinically-diagnosed tinnitus. Methods: Two tinnitus patients assessed the subjective similarity of their non-tonal tinnitus percepts and random auditory stimuli. Regression of the responses onto the stimuli yielded reconstructions which were evaluated qualitatively by playing back resynthesized waveforms to the subjects and quantitatively by response prediction analysis. Results: Subject 1 preferred their resynthesis to white noise; subject 2 did not. Response prediction balanced accuracies were significantly higher than chance across subjects: subject 1: 0.5963, subject 2: 0.6922. Conclusion: Reverse correlation can provide the foundation for reconstructing accurate representations of complex, non-tonal tinnitus in clinically diagnosed subjects. Further refinements may yield highly similar waveforms to individualized tinnitus percepts. (© 2024 The Authors.)
Databáze:	MEDLINE
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