Colonic schistosomiasis mimicking cancer, polyp, and inflammatory bowel disease: Five case reports and review of literature.

Autor: Mulate ST; Department of Internal Medicine, Addis Ababa University, College of Health Science, Addis Ababa 9086, Ethiopia. sebmulate@gmail.com., Nur AM; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Addis Ababa University, College of Health Science, Addis Ababa 9086, Ethiopia., Tasamma AT; Department of Internal Medicine, Addis Ababa University, College of Health Science, Addis Ababa 9086, Ethiopia., Annose RT; Department of Internal Medicine, Division of Gastroenterology and Hepatology, Addis Ababa University, College of Health Science, Addis Ababa 9086, Ethiopia., Dawud EM; Department of Internal Medicine, St Paul's Hospital Millennium Medical College, Addis Ababa 9086, Ethiopia., Ekubazgi KW; Department of Internal Medicine, Hawassa University, Hawassa PO Box 05, Ethiopia., Mekonnen HD; Department of Internal Medicine, St Paul's Hospital Millennium Medical College, Addis Ababa 1271, Ethiopia., Mohammed HY; Department of Pathology, Addis Ababa University, College of Health Science, Addis Ababa 9086, Ethiopia., Hailemeskel MB; Department of Pathology, St Paul's Hospital Millennium Medical College, Addis Ababa 1271, Ethiopia., Yimer SA; Department of Pathology, Ethio Tebib General Hospital, Addis Ababa 1111, Ethiopia.
Jazyk: angličtina
Zdroj: World journal of gastrointestinal endoscopy [World J Gastrointest Endosc] 2024 Aug 16; Vol. 16 (8), pp. 472-482.
DOI: 10.4253/wjge.v16.i8.472
Abstrakt: Background: Schistosomiasis, officially named as a neglected tropical disease by The World Health Organization, is a serious parasitic disease caused by trematode flukes of the genus Schistosoma . It is a common infectious disease, endemic in more than 78 countries. The disease can involve various organs and poses far-reaching public health challenges.
Case Summary: Here, we present a series of five patients with variable presentations: an asymptomatic patient who was diagnosed with colonic schistosomiasis upon screening colonoscopy; 2 patients with clinical suspicion of colonic cancer; and 2 patients with a clinical diagnosis of inflammatory bowel disease. All patients were subsequently confirmed to have colonic schistosomiasis after colonoscopy and histopathologic examination. The clinical manifestations, colonoscopy features and histologic findings of the patients are described. Most of the patients showed significant clinical improvement following administration of oral praziquantel.
Conclusion: Intestinal schistosomiasis can present with features mimicking other gastrointestinal conditions. This disease should be a diagnostic consideration in patients who live in or have traveled to endemic areas.
Competing Interests: Conflict-of-interest statement: The authors declare that there is no conflict of interest regarding the publication of this article.
(©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze: MEDLINE