Pediatric antiphospholipid syndrome: is it the same as an adult?

Autor:	Bitsadze V; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Khizroeva J; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Lazarchuk A; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Salnikova P; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Yagubova F; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Tretyakova M; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Grigoreva K; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Gashimova N; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Tsibizova V; The PREIS School (International and European School of Perinatal, Neonatal and Reproductive Medicine), Firenze, Italy., Karpova A; Moscow Healthcare Department, Vorokhobov City Clinical Hospital № 67, Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Health Ministry of Russian Federation, Moscow, Russia.; Health Ministry of Russian Federation, Yaroslavl State Medical University, Yaroslavl, Russia., Mostovoi A; Moscow Healthcare Department, Vorokhobov City Clinical Hospital № 67, Moscow, Russia.; Russian Medical Academy of Continuous Professional Education, Health Ministry of Russian Federation, Moscow, Russia.; Health Ministry of Russian Federation, Yaroslavl State Medical University, Yaroslavl, Russia., Kapanadze D; Center of Pathology of Pregnancy and Hemostasis «Medlabi», Tbilisi, Georgia., Voskresenskaya O; Department of Nervous Diseases and Neurosurgery, N.V. Sklifosovsky Institute of Clinical Medicine, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Akinshina S; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Di Renzo GC; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.; The PREIS School (International and European School of Perinatal, Neonatal and Reproductive Medicine), Firenze, Italy., Gris JC; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.; Faculty of Pharmaceutical and Biological Sciences, Montpellier University, Montpellier, France., Elalamy I; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.; Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France.; Hospital Tenon, Paris, France., Makatsariya A; Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children's Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Jazyk:	angličtina
Zdroj:	The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2024 Dec; Vol. 37 (1), pp. 2390637. Date of Electronic Publication: 2024 Aug 18.
DOI:	10.1080/14767058.2024.2390637
Abstrakt:	Importance: Antiphospholipid syndrome in neonates and children is a rare, but in some cases life-threatening condition with arterial and/or venous thrombosis and/or non-thrombotic neurological, skin, ophthalmological and other manifestations. Observations: This review highlights the available information about the features of pediatric APS, including the rare catastrophic form, the differences between pediatric and adult APS, and the role of genetic thrombophilia in APS manifestation. Conclusions and Relevance: The clinical manifestations and treatment options for APS in children may differ from those in adults, and prescribing therapy can be challenging due to the unique clinical and morphological characteristics of the pediatric patient. Pediatric APS may be a predictor of the development of certain autoimmune diseases and classic manifestations of APS in adulthood, therefore, a revision of the existing criteria for the diagnosis and treatment of APS in children is necessary.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu