Comparison of incident breast cancer cases in the largest national US tumor registries.

Autor: Plichta JK; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.; Department of Population Health Sciences, Duke University Medical Center, Durham, North Carolina, USA.; Duke Cancer Institute, Durham, North Carolina, USA., Thomas SM; Duke Cancer Institute, Durham, North Carolina, USA.; Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA., Chanenchuk TC; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA., Chan K; American College of Surgeons Cancer Programs, Chicago, Illinois, USA., Hyslop T; Department of Pharmacology, Physiology and Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Hwang ES; Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.; Duke Cancer Institute, Durham, North Carolina, USA., Greenup RA; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
Jazyk: angličtina
Zdroj: Cancer [Cancer] 2024 Aug 18. Date of Electronic Publication: 2024 Aug 18.
DOI: 10.1002/cncr.35525
Abstrakt: Background: This study compared incident breast cancer cases in the National Cancer Database (NCDB) and Surveillance, Epidemiology, End Results Program (SEER) to a national population cancer registry.
Methods: Patients with malignant or in situ breast cancer (BC) 2010-2019 in the NCDB and SEER were compared to the US Cancer Statistics (USCS). Case coverage was estimated as the number of patients in the NCDB/SEER as a proportion of USCS cases.
Results: The USCS reported 3,047,509 patients; 77.5% patients were included in the NCDB and 46.0% in SEER. Case ascertainment varied significantly by patient sex (both registries, p < .001). For males, 84.1% were captured in the NCDB, whereas only 77.5% of females were included. Case coverage in SEER was better for females than males (46.1% vs. 43.5%). Registries varied significantly by race/ethnicity (both p < .001). Case coverage in the NCDB was highest for non-Hispanic White (78.2%), non-Hispanic Black (77.7%), and non-Hispanic Asian or Pacific Islander (72.5%) BC patients, and lowest for Hispanic (56.4%) and non-Hispanic American Indian/Alaska Native (41.1%) patients. In SEER, case coverage was highest for non-Hispanic Asian or Pacific Islander (78.1%) and Hispanic (69.6%) patients and it was significantly lower for all other subgroups (non-Hispanic Black, 44.8%; non-Hispanic White, 42.4%; and non-Hispanic American Indian/Alaska Native, 36.6%).
Conclusions: National US tumor registries provide data for a large sampling of breast cancer patients, yet significant differences in case coverage were observed based on age, sex, and race/ethnicity. These findings suggest that analyses using these data sets and interpretation of findings should account for these meaningful variances.
(© 2024 American Cancer Society.)
Databáze: MEDLINE
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