VMT/ACP/Dextran composite nanosheets against dental caries through promoting mineralization of dentin tubules, pH buffering, and antibacterial.
Autor: | Xu Y; Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, National Center for Stomatology, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, No.639 Zhizaoju Road, Shanghai, 200011, China., Mou J; The Key Laboratory of Resource Chemistry of Ministry of Education, Shanghai Key College of Chemistry and Materials Science, Shanghai Normal University, Shanghai, 200234, China. moujuan@shnu.edu.cn., Dai J; Department of Oral and Cranio-Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, National Center for Stomatology, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, No.639 Zhizaoju Road, Shanghai, 200011, China. daijiewen@163.com. |
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Jazyk: | angličtina |
Zdroj: | Journal of nanobiotechnology [J Nanobiotechnology] 2024 Aug 17; Vol. 22 (1), pp. 490. Date of Electronic Publication: 2024 Aug 17. |
DOI: | 10.1186/s12951-024-02709-9 |
Abstrakt: | Dental caries is a worldwide public healthcare concern, and is closely related to the acidic environment that caused by bacterial decomposition of food. In this study, a two-step ion exchange liquid-phase stripping method was applied to strip out vermiculite (VMT) nanosheets, then amorphous calcium phosphate (ACP) and dextran were inserted between the VMT nanosheets interlayer to obtain a composite two-dimension nanosheets (VMT/ACP/Dextran). VMT/ACP/Dextran composite nanosheets exhibited excellent biocompatibility and could provide exogenous Ca 2+ and PO (© 2024. The Author(s).) |
Databáze: | MEDLINE |
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