An accelerated PETALUTE MRI sequence for in vivo quantification of sodium content in human articular cartilage at 3T.

Autor: Villarreal CX; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA., Shen X; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA.; Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94158, USA., Alhulail AA; Department of Radiology and Medical Imaging, Prince Sattam Bin Abdulaziz University, 16278, Al-Kharj, Saudi Arabia., Buffo NM; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA., Zhou X; College of Health and Human Sciences, Purdue University, West Lafayette, IN, 47907, USA., Pogue E; College of Health and Human Sciences, Purdue University, West Lafayette, IN, 47907, USA., Özen AC; Division of Medical Physics, Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany., Chiew M; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Physical Sciences, Sunnybrook Research Institute, Toronto, Canada.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Sawiak S; Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, UK., Emir U; College of Health and Human Sciences, Purdue University, West Lafayette, IN, 47907, USA.; Department of Radiology, School of Medicine, University of North Carolina, Chapel Hill, NC, 27599, USA., Chan DD; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA. chand@purdue.edu.; School of Mechanical Engineering, Purdue University, West Lafayette, IN, 47907, USA. chand@purdue.edu.
Jazyk: angličtina
Zdroj: Skeletal radiology [Skeletal Radiol] 2024 Aug 17. Date of Electronic Publication: 2024 Aug 17.
DOI: 10.1007/s00256-024-04774-5
Abstrakt: Objective: In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human articular cartilage in the knee.
Materials and Methods: We scanned five healthy subjects using a 3D dual-echo PETALUTE acquisition and two comparable implementations of 3D DA-radial spokes acquisitions, one matching the number of k-space projections (Radial - Matched Spokes) and the other matching the total number of samples (Radial - Matched Samples) acquired in k-space.
Results: The PETALUTE acquisition enabled equivalent sodium quantification in articular cartilage volumes of interest (168.8 ± 29.9 mM, mean ± standard deviation) to those derived from the 3D radial acquisitions (171.62 ± 28.7 mM and 149.8 ± 22.2 mM, respectively). We achieved a 41% shorter scan time of 2:06 for 3D PETALUTE, compared to 3:36 for 3D radial acquisitions. We also evaluated the feasibility of further acceleration of the PETALUTE sequence through retrospective compressed sensing with 2 × and 4 × acceleration of the first echo and showed structural similarity of 0.89 ± 0.03 and 0.87 ± 0.03 when compared to non-retrospectively accelerated reconstruction.
Conclusion: We demonstrate improved scan time with equivalent performance using a 3D dual-echo PETALUTE sequence compared to the 3D DA-radial sequence for sodium MRI of articular cartilage.
(© 2024. The Author(s).)
Databáze: MEDLINE
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