Pectin from steam explosion-treated citrus peel exhibits good emulsion properties and bioavailability-promoting effect in vitro of nobiletin.

Autor: Yang X; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China., Liu X; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China., Zhao S; School of Life Science, Shanxi University, Taiyuan 030006, China., Huo M; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China., Tian G; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China. Electronic address: fengxinzi.812@163.com., Sang Y; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China. Electronic address: sangyaxin@sina.com.
Jazyk: angličtina
Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 2), pp. 134758. Date of Electronic Publication: 2024 Aug 14.
DOI: 10.1016/j.ijbiomac.2024.134758
Abstrakt: Steam explosion (SE) is a potential method to modify pectin structure, which might be connected to its emulsifying characteristics and the bioavailability of encapsulated polymethoxyflavone like nobiletin. However, the relationship between SE-modified pectin and the bioavailability of encapsulated nobiletin is still unclear. In this study, nobiletin-loaded emulsion was fabricated using citrus pectin modified with SE (0.15-0.9 MPa, 3 min) as emulsifier for in vitro digestion study, and the transport and absorption of nobiletin in Caco-2 cells to investigate the bioavailability-promoting effect. The results showed that SE treatment lowered the droplet size of emulsion from 21.38 ± 2.30 μm to 2.14 ± 0.12 μm, enhanced the nobiletin encapsulation efficiency from 23.73 ± 0.78% to 86.27 ± 3.81%, improved the nobiletin bioaccessibility in vitro from 2.48 ± 0.10% to 25.42 ± 0.10% and increased the intracellular accumulation of nobiletin by over 10 times, even higher than that of Tween 80. In conclusion, pectin from SE-treated citrus peel exhibited good emulsion properties and bioavailability-promoting effect in vitro of nobiletin.
Competing Interests: Declaration of competing interest We declare that we do not have any commercial or associative interest that represents a conflict of interest in connection with the work submitted.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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